39156-41-7

Off-white to violet or dark brown powder. Emits toxic fumes of nitrogen oxides and sulfur oxides when heated to decomposition.

2,4-DIAMINOANISOLE SULFATE(39156-41-7) is weakly acidic. Can react as either an oxidizing agent or reducing agent.

Water soluble. Darkens on exposure to light.

The principal use of 2,4-diamino-ani- sole (and its salts such as the sulfate) as a component of oxidation (permanent) hair and fur dye formulations. Human exposure to 2,4-diaminoanisole sulfate may possibly occur through skin absorption at chemical and dye production facilities, as well as through dermal contact in persons using hair dyes containing the chemical.

Flash point data for this chemical are not available; however, 2,4-DIAMINOANISOLE SULFATE is probably combustible.

Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respira- tion with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with run- ning water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Medical obser- vation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatible with strong oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. The sulfate may react violently with aluminum and magnesium.

2,4-Diaminoanisole is a needle-like solid.

Dissolve or mix the material with a combustible solvent and burn in a chemical incinera- tor equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed .

2,4-Diaminoanisole sulfate has been used primarily as a component of oxidizing “permanent” hair- and fur-dye formulations. In 1978, about 75% of hair-dye formulations contained 2,4-diaminoanisole orits sulfate. However, a U.S. regulation requiring a warning label on allhair dyes containing 2,4-diaminoanisole or its sulfate was to become effective in April 1980, and the chemicals were voluntarily removed from products before that time (IARC 1982). 2,4-Diaminoanisole also has been used as an intermediate in the production of C.I. basic brown 2, which has been used to dye furs, acrylic fibers, cotton, wool, nylon, polyester, leather, and suede and has been an ingredient of shoe polishes (IARC 1978, 1982).

2,4-Diaminoanisole sulfate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.