SKQ1 (bromide) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).
1 SKQ1 prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer’s disease, as well as decreases severity of arthritic lesions in rats.
2,3 SKQ1 slows development of age-related ocular pathologies in murine, porcine, bovine, and canine model systems.
4 It also prevents acute phenoptosis following rhabdomyolysis, stroke, and myocardial infarction.
5,6,7