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N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Product Name:
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
CAS No.
24589-78-4
Chemical Name:
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
CBNumber:
CB0161574
Molecular Formula:
C6H12F3NOSi
Formula Weight:
199.25
MOL File:
24589-78-4.mol
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Property

Melting point:
98-100°C
Boiling point:
130132°C
Density 
1.075 g/mL at 25 °C(lit.)
vapor density 
>1 (vs air)
vapor pressure 
8.8 mm Hg ( 27 °C)
refractive index 
n20/D 1.383
Flash point:
77 °F
storage temp. 
2-8°C
pka
-1.34±0.70(Predicted)
form 
Liquid
color 
Clear colorless to light yellow
Specific Gravity
1.076
Water Solubility 
reacts
Sensitive 
Moisture Sensitive
Hydrolytic Sensitivity
7: reacts slowly with moisture/water
BRN 
1941550
InChIKey
MSPCIZMDDUQPGJ-UHFFFAOYSA-N
CAS DataBase Reference
24589-78-4(CAS DataBase Reference)
EPA Substance Registry System
Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4)
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Safety

Hazard Codes 
Xi,F,T,N
Risk Statements 
10-36/37/38-61-50/53-51/53
Safety Statements 
26-36-37/39-16-45-53-61
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
AC9800000
10-21
Hazard Note 
Flammable
TSCA 
T
HazardClass 
3
PackingGroup 
III
HS Code 
29319090
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N-Bromosuccinimide Price More Price(24)

Sigma-Aldrich Gold
Product number:
394866
Product name :
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
Purity:
synthesis grade
Packaging:
5ml
Price:
$84.2
Updated:
2019/12/02
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Buy
Sigma-Aldrich Gold
Product number:
394866
Product name :
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
Purity:
synthesis grade
Packaging:
10x1ml
Price:
$130
Updated:
2019/12/02
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TCI Chemical Gold
Product number:
M0672
Product name :
N-Methyl-N-trimethylsilyltrifluoroacetamide [Trimethylsilylating Agent]
Purity:
>95.0%(GC)
Packaging:
5mL
Price:
$44
Updated:
2019/12/02
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Buy
TCI Chemical Gold
Product number:
M0672
Product name :
N-Methyl-N-trimethylsilyltrifluoroacetamide [Trimethylsilylating Agent]
Purity:
>95.0%(GC)
Packaging:
25mL
Price:
$132
Updated:
2019/12/02
Buy:
Buy
Alfa Aesar Gold
Product number:
A13141
Product name :
N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%
Packaging:
25g
Price:
$153
Updated:
2019/12/02
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Buy
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to light yellow liquid

Uses

A new metabolite of Famprofazone in humans.

Uses

pharmaceutical intermediate

Definition

ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat sation agent used in gas chromatography/mass spectrometry applications.

Purification Methods

Fractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.]

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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Suppliers

Global(174)Suppliers
TCI AMERICA
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+1-800-423-8616 / +1-503-283-1681
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CovaChem, LLC.
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Alfa Chemistry
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24589-78-4, N-Methyl-N-(trimethylsilyl)trifluoroacetamideRelated Search:

Iodotrimethylsilane Azidotrimethylsilane Dichlorodimethylsilane Kresoxim-methyl Methyl Methyl bromide Hexamethyldisilane Methyltriacetoxysilane Methyl acetate Methyl acrylate FLUOROACETAMIDE Thiophanate-methyl Bensulfuron methyl N-Methylacetamide Trifluoroacetamide Trifluoroacetamidine TRIMETHYLSILANE Parathion-methyl
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  • 24589-78-4
  • 25489-78-4
  • 24589-44-7
  • CF3CONCH3SiCH33
  • C6F3H12NOSi
  • C6H12F3NOSi
  • C6H12F3NOS
  • Analytical Chromatography Product Catalog
  • Fluka Reagents
  • Derivatization Reagents
  • Synthetic Reagents