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Sulfasalazine Structure

Sulfasalazine

Chemical Properties

Melting point 260-265 °C (dec.)(lit.)
Boiling point 689.3±65.0 °C(Predicted)
Density  1.3742 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  NH4OH 1 M: 50 mg/mL, clear, red
pka pKa 0.6(H2O t = 20 I < 0.001) (Uncertain);2.4(H2O t = 20 I < 0.001) (Uncertain);9.7(H2O t = 20 I < 0.001) (Uncertain);11.8(H2O t = 20 I < 0.001) (Uncertain)
form  powder
color  Orange
Water Solubility  <0.1 g/100 mL at 25 ºC
Merck  14,8942
BRN  356241
BCS Class 2,4
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey NCEXYHBECQHGNR-QZQOTICOSA-N
CAS DataBase Reference 599-79-1(CAS DataBase Reference)
FDA UNII 3XC8GUZ6CB
IARC 2B (Vol. 108) 2016
Proposition 65 List Sulfasalazine (salicylazosulfapyridine)
NCI Drug Dictionary Azulfidine
ATC code A07EC01
EPA Substance Registry System Salicylazosulfapyridine (599-79-1)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H317-H334
Precautionary statements P261-P272-P280-P284-P302+P352-P333+P313
Hazard Codes  Xn
Risk Statements  42/43
Safety Statements  22-29/56-45
RIDADR  3077
WGK Germany  2
RTECS  VO6250000
8
HS Code  29350090
Hazardous Substances Data 599-79-1(Hazardous Substances Data)
Toxicity LD50 oral in rabbit: > 7500mg/kg
NFPA 704:
0
2 0

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Sulfasalazine Chemical Properties,Usage,Production

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Sulfasalazine Spectrum