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Chloramphenicol sodium succinate

Product Name:
Chloramphenicol sodium succinate
CAS No.
982-57-0
Chemical Name:
Chloramphenicol sodium succinate
CBNumber:
CB0406947
Molecular Formula:
C15H15Cl2N2O8.Na
Formula Weight:
445.19
MOL File:
982-57-0.mol
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Chloramphenicol sodium succinate Property

solubility 
H2O: soluble50mg/mL
form 
solid
InChIKey
RPLOPBHEZLFENN-HTMVYDOJSA-M
CAS DataBase Reference
982-57-0(CAS DataBase Reference)
EPA Substance Registry System
Chloramphenicol sodium succinate (982-57-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-36
WGK Germany 
3
RTECS 
AB6905000
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N-Bromosuccinimide Price More Price(4)

Sigma-Aldrich Gold
Product number:
C3787
Product name :
Chloramphenicol succinate sodium salt
Purity:
≥80% (HPLC)
Packaging:
5g
Price:
$52.6
Updated:
2019/12/02
Buy:
Buy
Sigma-Aldrich Gold
Product number:
C3787
Product name :
Chloramphenicol succinate sodium salt
Purity:
≥80% (HPLC)
Packaging:
25g
Price:
$210
Updated:
2019/12/02
Buy:
Buy
Sigma-Aldrich Gold
Product number:
C3787
Product name :
Chloramphenicol succinate sodium salt
Purity:
≥80% (HPLC)
Packaging:
100g
Price:
$575
Updated:
2019/12/02
Buy:
Buy
Sigma-Aldrich Gold
Product number:
C1425000
Product name :
Chloramphenicol sodium succinate
Purity:
European Pharmacopoeia (EP) Reference Standard
Packaging:
c1425000
Price:
$183
Updated:
2019/12/02
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Buy
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Chloramphenicol sodium succinate Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white powder, hygroscopic

Uses

antibacterial, antirickettsial, inhibits protein synthesis

Uses

Chloramphenicol succinate sodium is the salt prepared from chloramphenicol succinate using the free carboxylic acid of the succinate which ionises and readily forms in weakly sodium hydroxide solutions. The sodium salt is the preferred formulation for pharmaceutical applications, providing a more readily soluble product. Chloramphenicol succinate is significantly less active than chloramphenicol but acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.

General Description

White powder.

General Description

Chloramphenicol sodium succinate is the water-solublesodium salt of the hemisuccinate ester of chloramphenicol.Because of the low solubility of chloramphenicol, the sodiumsuccinate is preferred for intravenous administration. Theavailability of chloramphenicol from the ester followingintravenous administration is estimated to be 70% to 75%; theremainder is excreted unchanged. Poor availability ofthe active form from the ester following intramuscular injectionprecludes attaining effective plasma levels of the antibioticby this route. Orally administered chloramphenicol orits palmitate ester actually gives higher plasma levels of theactive antibiotic than does intravenously administered chloramphenicolsodium succinate. Nonetheless, effectiveconcentrations are achieved by either route.

Air & Water Reactions

Freely soluble in water.

Fire Hazard

Flash point data for Chloramphenicol sodium succinate are not available, but Chloramphenicol sodium succinate is probably combustible.

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Chloramphenicol sodium succinate Suppliers

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BeiJing Hwrk Chemicals Limted
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0539-6365991
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BOC Sciences
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Beijing HuaMeiHuLiBiological Chemical
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ChemStrong Scientific Co.,Ltd
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982-57-0, Chloramphenicol sodium succinateRelated Search:

Phenyltriethoxysilane Chloramphenicol hemisuccinate Sodium gluconate Dichlorodiphenylsilane Sodium hydroxide Diclofenac sodium Sodium bicarbonate Sodium formate 6alpha-Methylprednisolone sodium succinate Chloramphenicol sodium succinate N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE 2-Amino-1-(4-nitrophenyl)-1,3-propanediol (-)-Pseudoephedrine nitrosochloramphenicol 1-deoxychloramphenicol N-Methyl-4-nitrophenethylamine hydrochloride 3-PHENYL PROPYL PROPIONATE Dichloromethylphenylsilane
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  • PubChem ID: 656580
  • 982-57-0
  • C15H15Cl2N2O8Na
  • C15H15Cl2N2NaO8
  • BioChemical
  • Antibiotics
  • Antibiotics A to Z
  • Antibiotics A-F
  • GLOBENICOL