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Acetazolamide Structure

Acetazolamide

Chemical Properties

Melting point 258-259 °C
Density  1.610 (estimate)
refractive index  1.6270 (estimate)
storage temp.  2-8°C
solubility  Soluble in NH4OH (50 mg/mL), DMSO, Methanol and slightly soluble in Ethanol.
pka 7.2(at 25℃)
form  solid
color  White to Off-White
Water Solubility  <0.1 g/100 mL at 22 ºC
λmax 265nm(H2O)(lit.)
Merck  14,53
BRN  212994
BCS Class 4
Stability Hygroscopic
InChIKey BZKPWHYZMXOIDC-UHFFFAOYSA-N
CAS DataBase Reference 59-66-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII O3FX965V0I
Proposition 65 List Acetazolamide
NCI Drug Dictionary Diamox
ATC code S01EC01
NIST Chemistry Reference 2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide(59-66-5)
EPA Substance Registry System Acetazolamide (59-66-5)

Safety

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319
Precautionary statements P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36
RIDADR  2811
WGK Germany  2
RTECS  AC8225000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29350090
Hazardous Substances Data 59-66-5(Hazardous Substances Data)
Toxicity LD50 oral in mouse: 4300mg/kg
NFPA 704:
1
2 0

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