Calcium gluconate Property

Melting point:

195°C

alpha 

10.2 º (c=1, H2O 22 ºC)

solubility 

Sparingly soluble in water, freely soluble in boiling water.

form 

Crystals or Crystalline Powder

color 

White

PH

pH;6.0～8.0

Water Solubility 

3.3 g/100mL

Hydrolytic Sensitivity

0: forms stable aqueous solutions

Merck 

14,1669

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

KYUVBRZSDFBLTH-OSQBQZLYSA-M

CAS DataBase Reference

299-28-5(CAS DataBase Reference)

EPA Substance Registry System

D-Gluconic acid, calcium salt (2:1) (299-28-5)

Safety

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

24/25-36-26

WGK Germany 

1

RTECS 

EW2100000

TSCA 

No

HS Code 

29181600

Hazardous Substances Data

299-28-5(Hazardous Substances Data)

Calcium gluconate Chemical Properties,Usage,Production

Description

Calcium gluconate is the calcium salt of gluconate, being an oxidative product of glucose containing 9.3% calcium. Calcium gluconate is a kind of mineral supplement and medication. It can be used for vein injection to treat the low blood calcium, high blood potassium, and magnesium toxicity. It is required only when there is not enough calcium in the diet. It is also used for the treatment of black widow spider bites to relieve muscle cramping and treatment of osteoporosis or rickets. It can also be used to decrease the capillary permeability in allergic conditions, nonthrombocytopenic purpura and exudative dermatoses.

References

http://www.drugbank.ca/drugs/DB11126 https://en.wikipedia.org/wiki/Calcium_gluconate

Chemical Properties

white crystalline powder or granules

Uses

analgesic, antipyretic

Uses

Calcium Gluconate is used as an inert ingredient in pesticide formulations applied to crops. It is also used as a supplement to fortify beverages and foods lacking a sufficient amount of calcium.

Uses

In sewage purification; in coffee powders to prevent caking.

Uses

Calcium Gluconate is a white crystalline granule or powder that functions as a firming agent, formulation aid, sequestrant, and sta- bilizer. at room temperature the anhydrous form has a solubility of approximately 1 g in 30 ml of water, which improves in boiling water to approximately 1 g in 5 ml of water. it also exists as calcium gluconate (monohydrate). it is used as a source of calcium ions for sodium alginate gels, and as a calcium fortifier in baked goods, pud- dings, and dairy product analogs. it functions as a coagulation aid in milk and instant pudding powders and as a means of masking the bitter aftertaste of some artificial sweeteners.

brand name

Calglucon (Novartis).

Industrial uses

calcium gluconate [Ca(C₆H₁₁O₇)₂] is used as a food additive in vitamin pills.injection of a 10% calcium gluconate has been recommended. It has to be kept in mind that the plasma Ca²⁺ level and any changes to the electrocardiogram (ECG) have to be carefully monitored.

Safety Profile

Moderately toxic by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects in infants by intramuscular route: dermatitis and fever. When heated to decomposition it emits acrid smoke and fumes. See also CALCIUM COMPOUNDS.

Veterinary Drugs and Treatments

Calcium salts are used for the prevention or treatment of hypocalcemic conditions.

Purification Methods

Dissolve it in H2O, filter and precipitate it by adding MeOH. Filter off the solid and dry it in a vacuum at 85o. Alternatively, dissolve it in H2O, filter (from insoluble inorganic Ca) and evaporate it to dryness under vacuum at 85o. [March et al. J Am Pharm Assoc 41 366 1952, Beilstein 3 IV 1255.]