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Ribavirin Structure

Ribavirin

Chemical Properties

Melting point 174-176°C
alpha  D25 -36.5° (c = 1 in water); D20 -38° (c = 1 in water)
Boiling point 387.12°C (rough estimate)
Density  1.4287 (rough estimate)
refractive index  -36 ° (C=1, H2O)
storage temp.  2-8°C
solubility  Freely soluble in water, slightly soluble in ethanol (96 per cent), slightly soluble or very slightly soluble in methylene chloride. It shows polymorphism (5.9).
form  White solid
pka 12.95±0.70(Predicted)
color  White
Water Solubility  >=10 g/100 mL at 19 ºC
Merck  14,8198
BCS Class 3
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
InChIKey IWUCXVSUMQZMFG-AFCXAGJDSA-N
LogP -2.260 (est)
CAS DataBase Reference 36791-04-5
FDA UNII 49717AWG6K
NCI Dictionary of Cancer Terms ribavirin
NCI Drug Dictionary Rebetol
ATC code J05AP01
Proposition 65 List Ribavirin
EPA Substance Registry System Ribavirin (36791-04-5)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H341-H360FD
Precautionary statements P201-P308+P313
Hazard Codes  T,Xi
Risk Statements  61-36/38
Safety Statements  53-22-45-37/39-26
WGK Germany  3
RTECS  XZ4250000
HS Code  29349990
Hazardous Substances Data 36791-04-5(Hazardous Substances Data)
Toxicity LD50 i.p. in mice: 1.3 g/kg; orally in rats: 5.3 g/kg (Witkowski, 1972)
NFPA 704:
0
2 0

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