ChemicalBook > CAS DataBase List > Ethyl 4,4,4-trifluoroacetoacetate

Ethyl 4,4,4-trifluoroacetoacetate

Product Name:
Ethyl 4,4,4-trifluoroacetoacetate
CAS No.
372-31-6
Chemical Name:
Ethyl 4,4,4-trifluoroacetoacetate
CBNumber:
CB1133091
Molecular Formula:
C6H7F3O3
Formula Weight:
184.11
MOL File:
372-31-6.mol
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Ethyl 4,4,4-trifluoroacetoacetate Property

Melting point:
-39 °C
Boiling point:
129-130 °C(lit.)
Density 
1.259 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.375(lit.)
Flash point:
84 °F
storage temp. 
Flammables area
solubility 
10g/l
pka
7.76±0.10(Predicted)
form 
Liquid
color 
Clear colorless to slightly yellow
Specific Gravity
1.259 (20/4℃)
PH
6.2 (10g/l, H2O, 20℃)
Water Solubility 
10 g/L (20 ºC)
BRN 
608353
InChIKey
OCJKUQIPRNZDTK-UHFFFAOYSA-N
CAS DataBase Reference
372-31-6(CAS DataBase Reference)
NIST Chemistry Reference
Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester(372-31-6)
EPA Substance Registry System
Ethyl 4,4,4-trifluoroacetoacetate (372-31-6)
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Safety

Hazard Codes 
Xn,F,C,Xi
Risk Statements 
10-22-52/53
Safety Statements 
61-16
RIDADR 
UN 3272 3/PG 3
WGK Germany 
2
Hazard Note 
Flammable/Corrosive
TSCA 
T
HazardClass 
3
PackingGroup 
III
HS Code 
29183000
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N-Bromosuccinimide Price More Price(11)

Sigma-Aldrich Gold
Product number:
689106
Product name :
Ethyl 4,4,4-trifluoroacetoacetate
Purity:
Lonza quality, ≥98.0% (GC)
Packaging:
5kg
Price:
$2900
Updated:
2018/11/13
Buy:
Buy
Sigma-Aldrich Gold
Product number:
689106
Product name :
Ethyl 4,4,4-trifluoroacetoacetate
Purity:
Lonza quality, ≥98.0% (GC)
Packaging:
25kg
Price:
$8630
Updated:
2018/11/13
Buy:
Buy
TCI Chemical Gold
Product number:
T0810
Product name :
Ethyl 4,4,4-Trifluoroacetoacetate
Purity:
>98.0%(GC)
Packaging:
25g
Price:
$74
Updated:
2020/06/24
Buy:
Buy
TCI Chemical Gold
Product number:
T0810
Product name :
Ethyl 4,4,4-Trifluoroacetoacetate
Purity:
>98.0%(GC)
Packaging:
100g
Price:
$220
Updated:
2020/06/24
Buy:
Buy
Alfa Aesar Gold
Product number:
A13717
Product name :
Ethyl trifluoroacetoacetate, 98+%
Packaging:
50g
Price:
$128
Updated:
2020/06/24
Buy:
Buy
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Ethyl 4,4,4-trifluoroacetoacetate Chemical Properties,Usage,Production

Chemical Properties

Clear liquid

Uses

Intermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet

Uses

Widely used in the synthetic process of medicine, pesticides and organic intermediate.

Uses

Ethyl 4,4,4-trifluoroacetoacetate is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.

Ethyl 4,4,4-trifluoroacetoacetate Preparation Products And Raw materials Raw materials

Raw materials

Preparation Products

6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97% 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE (5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE (1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHANOL 4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE 7-HYDROXY-4-(TRIFLUOROMETHYL)COUMARIN ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL 4-BROMO-6-(TRIFLUOROMETHYL)PYRIMIDINE (5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL 1-PHENYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE THIFLUZAMIDE Ethyl 3-amino-4,4,4-trifluorocrotonate 4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE ETHYL 1-(TERT-BUTYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE 1-PHENYL-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE 4-Methylpyrimidine 4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97% (6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97% Ethyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97% Coumarin 151 ETHYL 2-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE (5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANAMINE 2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline 6-FLUORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE (4-(Trifluoromethyl)quinolin-2-yl)methanol ,97% ETHYL 3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE 4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97% 4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE (5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANOL 4-bromo-2-(trifluoromethyl)quinoline 4-(Trifluoromethyl)quinolin-2-amine 2-BROMO-4-(TRIFLUOROMETHYL)QUINOLINE 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone 4-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLIC ACID 5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXAMIDE 5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE 2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
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Ethyl 4,4,4-trifluoroacetoacetate Suppliers

Global(398)Suppliers
Shandong Zhanhua Yonghao Pharmaceutical Technology Co., Ltd.
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0576-88685096-
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13989620089@126.com
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Taizhou Yongfeng Chemical Industry Co., Ltd
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0576-88685096
Fax:
0086-576-88685099
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sales@yfchem.cn
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Nanjing Apicci Pharmaceutical Technology Co., Ltd.
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;
Fax:
QQ3590429773
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3590429773@qq.com;977144864@qq.com
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West fluorine technology co., ltd
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Yangzhou modier Electronic Materials Co., Ltd
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Wuhan EnTai Technology Development Co,.Ltd
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372-31-6, Ethyl 4,4,4-trifluoroacetoacetateRelated Search:

Ethyl acetoacetate Ethyl 2-chloroacetoacetate Ethylparaben Methyl acetoacetate Ethyl formate Ethyl bromodifluoroacetate Ethanol Acetoxyacetic acid Ethyl cellulose Ethyl trifluoroacetate Ethyl 4-chloroacetoacetate Ethyl 4-bromoacetoacetate CHLOROETHANE Ethylbenzene Ethyl acetate Ethyl acrylate Ethyl 2-methylacetoacetate Diethyl ether
  • Ethyl4,4,-Trifluoroacetoacetate
  • Ethyltrifluoroacetoacetate,98+%
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  • ETFAA
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  • Ethyl 3-oxo-4,4,4-trifluorobutanoate
  • Ethyl 4,4,4-trifluoro-3-oxobutyrate
  • (Trifluoroacetyl)acetic acid ethyl ester
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  • 4,4,4-Trifluoro-3-oxobutyric acid ethyl ester
  • Trifluoroacetylacetic acid ethyl ester
  • Ethyl 4,4,4-trifluoroacetoacetate 98%
  • Ethyl4,4,4-trifluoroacetoacetate98%
  • Ethyl 4,4,4-trifluoroacetoacetate,Ethyl 3-oxo-4,4,4-trifluorobutyrate
  • Ethyl 4,4,4-trifluoro-3-oxobutanoate, 97%+
  • Ethyl 4,4,4-trifluoro-3-oxobutanoate, 95%+
  • ETHYL TRIFLUOROACETOACETATE 98%
  • Ethyl 4,4,4-trifluoroacetoacetate,97%
  • Ethyl 2-(trifluoroacethyl)acetate
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  • ETHYL 3-OXO-4,4,4-TRIFLUOROACETOACETATE
  • ETHYL 3-OXO,4,4,4-TRIFLUOROBUTYRATE
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  • TIMTEC-BB SBB008825
  • 4,4,4-TRIFLUORO-3-OXOBUTANOIC ACID ETHYL ESTER
  • 4,4,4-TRIFLUOROACETOACETIC ACID ETHYL ESTER
  • AKOS B020306
  • 4,4,4-trifluoro-3-oxo-butanoicaciethylester
  • Acetoacetic acid, 4,4,4-trifluoro-, ethyl ester
  • Acetoacetic acid, 4-trifluoro-, ethyl ester
  • Butanoicacid,4,4,4-trifluoro-3-oxo-,ethylester
  • Ethyl (trifluoroacetyl)acetate
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  • Ethyl 4,4,4-trifluor
  • TRIFLUOROACETOACETIC ACID ETHYL ESTER
  • Ethyl 4,4,4-trifluoroacetocaetate
  • Ethyl 4,4,4-trifluoroaceto
  • 4,4,4- threefluorideethyl acetoacetate
  • Trifluoro ethyl acetoacetate
  • 4,4,4-Trifluoro-3-oxo-butyric acid ethyl ester (Ethyl trifluoroacetoacetate)
  • Ethyl 4,4,4-trifluoro-3-oxobutanoate, Ethyl 4,4,4-trifluoro-3-oxobutyrate
  • Ethyl 3-oxo-4,4,4-trifluorobutyrate Ethyl 4,4,4-trifluoro-3-oxobutanoate 4,4,4-Trifluoroacetoacetic Acid Ethyl Ester
  • 4-trifluoroacetoacetate
  • Ethyl4,4,4-trifluoroacetoacetate (ETFAA)
  • 4,4,4-trifL
  • uoroacetoacetate
  • 372-31-6
  • 373-31-6
  • 371-31-6
  • CF3COCH2COOC2H5
  • C6H7F3O3
  • CF3COCH2CO2C2H5
  • ACETATE