Propargyl-PEG8-NHS ester
- Product NamePropargyl-PEG8-NHS ester
- CAS2182601-74-5
- CBNumberCB24849485
- MFC24H39NO12
- MW533.57
- MDL NumberMFCD31536764
- MOL File2182601-74-5.mol
Chemical Properties
| Boiling point | 593.4±60.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| solubility | Soluble in DCM |
Propargyl-PEG8-NHS ester Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| BroadPharm BP-23778 | 100mg | $320 | Propargyl-PEG8-NHSester 98% |
Buy |
| Activate Scientific AS107809 | 250mg | $454 | Propargyl-PEG7-CH2CH2COONHS 97% |
Buy |
| BroadPharm BP-23778 | 500mg | $720 | Propargyl-PEG8-NHSester 98% |
Buy |
| Acrotein B-1545 | 0.25g | $315.33 | Propargyl-PEG7-CH2CH2COONHS 97% |
Buy |
Propargyl-PEG8-NHS ester Chemical Properties,Usage,Production
Description
Propargyl-PEG8-NHS ester is an amine reactive compound with an alkyne group. The alkyne group reacts with azide-containing biomolecules in Click Chemistry reactions, copper is needed as a catalyst. The hydrophilic PEG units helps the compound to have better solubility in aqueous environment.Biological Activity
Propargyl-PEG8-NHS ester is a PROTAC bridge, belonging to the PEG class and the Alkyl/ether class. It can be used to synthesize a range of PROTAC molecules. And it is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
| PEGs
| Alkyl/ether
|
Preparation Products And Raw materials
Propargyl-PEG8-NHS ester Suppliers
Global(38)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 | |
| +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 | |
| 027-65563561 18717150066 |
3207347307@qq.com | CHINA | 1238 | 58 | |
| +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9635 | 58 | |
| 571-86758373 +8613588754946 |
sales@huarongpharm.com | CHINA | 3149 | 58 | |
| +undefined18143011203 | info@chemextension.com | China | 42057 | 58 | |
| +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2996 | 58 | |
| +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 | |
| 021-61551611 13296011611 |
contact@trustwe.com | China | 9900 | 58 | |
| 400-1647117 15221909166 |
product02@bidepharm.com | China | 41438 | 60 |
View Lastest Price from Propargyl-PEG8-NHS ester manufacturers
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