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Sulfamide

Product Name:
Sulfamide
CAS No.
7803-58-9
Chemical Name:
Sulfamide
CBNumber:
CB2488651
Molecular Formula:
H4N2O2S
Formula Weight:
96.11
MOL File:
7803-58-9.mol
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Sulfamide Property

Melting point:
90-92 °C(lit.)
Density 
1.611 g/mL at 25 °C(lit.)
storage temp. 
Refrigerator
solubility 
water: soluble50mg/mL, clear, colorless to faintly yellow
pka
10.87±0.60(Predicted)
form 
Crystalline Powder, Free From Visible Impurities
color 
White to practically white , free from visible impurities
Water Solubility 
soluble
Sensitive 
Moisture Sensitive
Merck 
14,8922
InChIKey
NVBFHJWHLNUMCV-UHFFFAOYSA-N
CAS DataBase Reference
7803-58-9(CAS DataBase Reference)
NIST Chemistry Reference
Sulfamide(7803-58-9)
EPA Substance Registry System
Sulfamide (7803-58-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
9
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
28530090
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N-Bromosuccinimide Price More Price(9)

Sigma-Aldrich Gold
Product number:
211370
Product name :
Sulfamide
Purity:
99%
Packaging:
5g
Price:
$97.1
Updated:
2019/12/02
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Buy
Sigma-Aldrich Gold
Product number:
211370
Product name :
Sulfamide
Purity:
99%
Packaging:
25g
Price:
$302
Updated:
2019/12/02
Buy:
Buy
TCI Chemical Gold
Product number:
S0890
Product name :
Sulfamide
Purity:
>96.0%(N)
Packaging:
25g
Price:
$26
Updated:
2020/06/24
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Buy
TCI Chemical Gold
Product number:
S0890
Product name :
Sulfamide
Purity:
>96.0%(N)
Packaging:
250g
Price:
$135
Updated:
2020/06/24
Buy:
Buy
Alfa Aesar Gold
Product number:
A18680
Product name :
Sulfamide
Purity:
99%
Packaging:
2.5g
Price:
$44.4
Updated:
2020/06/24
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Buy
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Sulfamide Chemical Properties,Usage,Production

Description

Sulfamide is a white solid substance that is normally produced by reacting sulfuryl chloride with ammonia. Sulfamide is stable under normal conditions and soluble in acetone and DMSO. Sulfamide may also refer to the functional group in organic chemistry, and it consists of at least one group attached to a nitrogen atom of sulfamide.
It is a carbonic anhydrase inhibitor and is widely used as a pharmaceutical intermediate.
Sulfamide is sensitive to moisture, thus should be kept away from water and humidity. It should also be stored away from oxidizing agents. Sulfamide should be kept in a tightly closed container and placed in a cool, dry, and well-ventilated condition.

Chemical Properties

White Solid

Uses

Similar to urea in many of its reactions, but is more acidic, and can act as a dibasic acid.

Uses

A carbonic anhydrase inhibitor; used for treatment of cancer.

Uses

Sulfamide and its derivatives can also be used to prepare fused thiadiazine systems, Reaction with 2-aminoacetophenones affords IH-2,1,3-benzothia- diazine 2,2-dioxides 77 (65JOC3960). The corresponding 3,4-dihydro deriv- atives are readily available from 2-aminobenzylamines with either sulfuryl chloride (70M1443) or sulfamide (66USP3278532; 71MI055). These kinds of compounds can also be obtained from N-aryl-N'-alkylsulfamides and s-trioxane in a reaction involving cyclization by intramolecular sulfamido- methylation (79JOC2032) (Scheme 30).

Definition

ChEBI: The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to two amino groups and by double bonds to two oxygen atoms.

Purification Methods

Crystallise sulfamide from absolute EtOH. It decomposes at 250o. [Schenk in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I pp 482-483 1963.]

Sulfamide Preparation Products And Raw materials Raw materials

Raw materials

Preparation Products

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Sulfamide Suppliers

Global(245)Suppliers
Creasyn Finechem(Tianjin) Co., Ltd.
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022-83945878-
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022-83945176
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export@creasyn.com
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China
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715
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Wuhan EnTai Technology Development Co,.Ltd
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86-27-82330560
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86-27-82330547
Email:
2536851935@qq.com
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351
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J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Fax:
86-10-82849933
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Country:
China
ProdList:
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Fax:
86-21-61259102
Email:
sh@meryer.com
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China
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40268
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62
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801
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86-21-50328109
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3bsc@sina.com
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15880
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Alfa Aesar
Tel:
400-610-6006; 021-67582000
Fax:
021-67582001/03/05
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TAIYUAN RHF CO.,LTD.
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TCI (Shanghai) Development Co., Ltd.
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021-67121386 / 800-988-0390
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Beijing dtftchem Technology Co., Ltd.
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7803-58-9, SulfamideRelated Search:

4-(3'-Methylphenyl)amino-3-pyridinesulfonamide [3-[[[2-(DIAMINOMETHYLENEAMINO)-4-THIAZOLYL]METHYL]THIO]PROPIONYL]SULFAMIDE Famotidine N,N-DIMETHYL-N'-(2-MORPHOLINOETHYL)SULFAMIDE TOLYLFLUANID 3,5-DIMETHYL-2H-1,2,6-THIADIAZINE-1,1-DIONE 1,1'-Sulfonyldiimidazole 5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-2H-1,2,6-THIADIAZINE-1,1-DIONE 3-METHYL-5-(TRIFLUOROMETHYL)-2H-1,2,6-THIADIAZINE-1,1-DIONE 2-[(dimethylsulfamoyl)amino]-3-methylbutanoic acid RARECHEM AQ A1 0064 (S,S)-(-)-N,N'-BIS(ALPHA-METHYLBENZYL)SULFAMIDE (R,R)-(+)-N,N'-BIS(ALPHA-METHYLBENZYL)SULFAMIDE Burgess reagent Bentazone N,N,N',N'-TETRAETHYLSULFAMIDE N-(2-([(DIMETHYLAMINO)SULFONYL]AMINO)ETHYL)-2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZENECARBOXAMIDE Sulfanilamide
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Description