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Berberine hydrochloride

Product Name:
Berberine hydrochloride
CAS No.
633-65-8
Chemical Name:
Berberine hydrochloride
CBNumber:
CB3758777
Molecular Formula:
C20H18ClNO4
Formula Weight:
371.81
MOL File:
633-65-8.mol
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Berberine hydrochloride Property

Melting point:
204-206 °C (dec.)
storage temp. 
+2C to +8C
solubility 
methanol: soluble
form 
Yellow powder
Colour Index 
75160
color 
Yellow powder
Water Solubility 
SOLUBLE IN COLD WATER
BRN 
3836585
InChIKey
VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference
633-65-8
EPA Substance Registry System
Berberine chloride (633-65-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
RIDADR 
1544
WGK Germany 
2
RTECS 
DR9866400
3-10
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29349990
Toxicity
LD50 orl-rat: >15 g/kg KSRNAM 8,654,74
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N-Bromosuccinimide Price More Price(14)

Sigma-Aldrich Gold
Product number:
200275
Product name :
Berberine Chloride
Purity:
A highly potent and selective oxysterol EBI2 (GPR183) agonist (K
Packaging:
25mg
Price:
$31.4
Updated:
2019/12/02
Buy:
Buy
Sigma-Aldrich Gold
Product number:
1065210
Product name :
Berberine Chloride
Purity:
United States Pharmacopeia (USP) Reference Standard
Packaging:
50mg
Price:
$516.95
Updated:
2019/12/02
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Buy
Alfa Aesar Gold
Product number:
J62311
Product name :
Berberine chloride
Packaging:
5g
Price:
$37.1
Updated:
2020/06/24
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Sigma-Aldrich Gold
Product number:
B3251
Product name :
Berberine chloride form
Packaging:
5g
Price:
$42.7
Updated:
2019/12/02
Buy:
Buy
Sigma-Aldrich Gold
Product number:
B3251
Product name :
Berberine chloride form
Packaging:
10g
Price:
$81.5
Updated:
2019/12/02
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Buy
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Berberine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant

Uses

An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs.

Uses

An ingredient in some commercial eyewash products.

Safety Profile

Poison by intraperitoneal route.Slightly toxic by ingestion. Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx andCl-.

Purification Methods

Berberine chloride crystallises from water to give the dihydrate. The anhydrous salt may be obtained by recrystallisation from EtOH/Et2O, wash the crystals with Et2O and dry them in a vacuum. The iodide has m 250o(dec) (from EtOH). [Perkin J Chem Soc 113 503 1918, Kametani et al. J Chem Soc(C) 2036 1969, Beilstein 27 I 515, 27 II 567.]

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Berberine hydrochloride Suppliers

Global(371)Suppliers
Shanghai ChengShao Biological Technology Co., Ltd.
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021-61847300 13341622919
Fax:
021-61847300
Email:
shcss01@163.com
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China
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4810
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Shanghai Zheyuan Chemical Co., Ltd.
Tel:
Email:
my_furongdi@163.com
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China
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25
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58
Xiangtan Jiayeyuan Biotechnology Co., Ltd.
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0731-55570935-
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0731-55570935
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fiona1@yccreate.com
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China
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6885
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J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
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86-10-82849933
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jkinfo@jkchemical.com;market6@jkchemical.com
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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86-21-61259102
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sh@meryer.com
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40268
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INTATRADE GmbH
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+49 3493/605464
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+49 3493/605470
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future industrial shanghai co., ltd
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Chembest Research Laboratories Limited
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BeiJing Hwrk Chemicals Limted
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