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Isothiazolinones

Product Name:
Isothiazolinones
CAS No.
26172-55-4
Chemical Name:
Isothiazolinones
CBNumber:
CB4132565
Molecular Formula:
C4H4ClNOS
Formula Weight:
149.6
MOL File:
26172-55-4.mol
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Isothiazolinones Property

Melting point:
42-45?C
Boiling point:
109.7°C
Density 
1.25 (14% aq.)
refractive index 
n20/D 1.378
storage temp. 
Refrigerator
pka
-4.06±0.40(Predicted)
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
26172-55-4(CAS DataBase Reference)
NIST Chemistry Reference
5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4)
EPA Substance Registry System
5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)
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Safety

Hazard Codes 
C,N,T,Xn
Risk Statements 
34-43-50-20/21/22-50/53-23/24/25-42/43
Safety Statements 
26-36/37/39-45-60-61-24-28-36/37-23
RIDADR 
UN 1760 8/PG 2
WGK Germany 
1
RTECS 
NX8156850
HazardClass 
8
PackingGroup 
III
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N-Bromosuccinimide Price More Price(1)

Sigma-Aldrich Gold
Product number:
PHR1597
Product name :
CMIT/MIT
Purity:
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging:
1ml
Price:
$63.7
Updated:
2019/12/02
Buy:
Buy
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Isothiazolinones Chemical Properties,Usage,Production

Description

Isothiazolinone is a heterocyclic chemical compound related to isothiazole. Isothiazolinone is an antimicrobial preservative that is often used to control fungi, bacteria, and algae. Since water-containing solutions are the breeding grounds for bacteria, isothiazolinone can easily be used in such solutions.

Applications

Although isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials. Notably, various products that use isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions. Isothiazolinones is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.

Safety Information

The recommended use of isothiazolinone products by the manufacturers used as wrinkle releaser is not harmful. However, allergy to skin is one of the most reported issue with isothiazolinone.

Chemical Properties

Liquid

Uses

Isocil(R) MW-14 is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions. Suggested applications: preservative concentrate. Very low level.

Uses

Isocil(R) PC is a cost-effective antimicrobial for personal care formulations. Suggested applications: personal care preservative.

Uses

Isocil(R) RW is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems. Suggested applications: Industrial water treatment. Very low use levels.

Uses

A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.

Definition

ChEBI: A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.

Isothiazolinones Preparation Products And Raw materials Raw materials

Raw materials

Preparation Products

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Isothiazolinones Suppliers

Global(236)Suppliers
Shanghai SMEC Trading Co., Ltd.
Tel:
021-68640333
Fax:
(86-21)50893389
Email:
yuanqi@shanghaismec.com
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China
ProdList:
39
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55
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel:
0751-2828607-
Fax:
0751-2828607
Email:
3007432263@qq.com;
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China
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10503
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58
Weifang Kaihong Chemical Limited
Tel:
536-8865335
Fax:
86-536-5310398
Email:
sophia@kaihongchem.com
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China
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62
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55
Tianjin Zhongxin Chemtech Co., Ltd.
Tel:
022-66880623;022-89880623
Fax:
86(0)22-66880086
Email:
sales@tjzxchem.com;sales@tjzxchem.com
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China
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579
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60
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Fax:
86-10-82849933
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Country:
China
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96815
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76
INTATRADE GmbH
Tel:
+49 3493/605464
Fax:
+49 3493/605470
Email:
sales@intatrade.de
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Germany
ProdList:
3579
Advantage:
66
TAIYUAN RHF CO.,LTD.
Tel:
+86 351 7031519
Fax:
+86 351 7031519
Email:
sales@RHFChem.com
Country:
China
ProdList:
2348
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56
BeiJing Hwrk Chemicals Limted
Tel:
010-57411839-
Fax:
021-55236763
Email:
bjsales@hwrkchemical.com
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China
ProdList:
18708
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55
Beijing Ouhe Technology Co., Ltd
Tel:
010-82967028-
Fax:
+86-10-82967029
Email:
2355560935@qq.com
Country:
China
ProdList:
12495
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26172-55-4, IsothiazolinonesRelated Search:

2-tert-Butyl-5-chloroisothiazol-3(2H)-one 5-Chloro-2-n-octyl-4-isothiazolin-3-one Isothiazolinones Paraquat dichloride 5-Chloro-2-methyl-3(2H)-isothiazolone with 2-methyl-3(2H)-isothiazolone Methylparaben Kresoxim-methyl Acetonitrile Methylisothiazolinone Basic Violet 1 Methyl acetate Methyl acrylate Methyl Methanol Difluorochloromethane 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one 1,2-Benzisothiazol-3(2H)-one Kathon
  • 4-Isothiazolin-3-one,5-chloro-2-methyl-
  • 5-chloro-2-methyl-3(2h)-isothiazolon
  • 5-chloro-2-methyl-4-isothiazolin-3-on
  • Isothiazolinone
  • 5-Chloro-2-methyl-4-isothiazolinone
  • 5-CHLORIDE-2-METHYL-4-ISOTHIAZOLINE-3-KETONE
  • 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (CMI)
  • 5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLONE MIXED WITH 2-METHYL-3(2H)ISOTHIAZOLONE
  • Methychloroisothiazolinone/Methylisothiazolinone
  • 5-Chloro-2-Methyl-3(2H)-IsothiazoneMixedWith2-Methyl-3(2H)-Isothiazolone
  • 5-Chloro-2-Methyl-3(2H)-Isothiazone
  • 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (CMIT)
  • Chloromethylisothiazolinone
  • Chloromethylisothiazolone
  • CMI
  • CMIT
  • Danisol-K
  • MCI
  • Methylchloroisothiazolone
  • 3(2H)-Isothiazolone, 5-chloro-2-methyl-
  • 3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone
  • CMIT/MIT MIXTURE
  • Isothiazolinones
  • CMIT/MIT
  • 2-METHYL-5-CHLORO-4-ISO-THIAZOLINE-3-ONE
  • 5-Chloro-2-methyl-Isothiazolin-3-one/ 2-Methyl-Isothiazolin-3-one(CMIT/MIT)
  • 5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLE
  • METHYLCHLOROISOTHIAZOLINONE/METHYLISOTHIAZOLINONE
  • 5-CHLORO-2-METHYL-ISOTHIAZOLIN-3(2H)-ONE
  • 5-CHLORO-2-METHYLISOTHIAZOLINONE
  • 5-CHLORO-2-METHYL-2,3-DIHYDROISOTHIAZOL-3-ONE
  • METHYL/CHLOROMETHYLISOTHIAZOLINONE
  • 2-METHYL-5-CHLOROISOTHIAZOLIN-3-ONE
  • 5-CHLORO-2-METHYLISOTHIAZOLIN-3-ONE
  • KATHON886F
  • KATHONFP
  • CHLOROMETHYLISOTHIAZOLINE
  • METHYL(CHLORO)ISOTHIAZOLINONEMIXTURE
  • KATHON886MW
  • KATHONLX
  • CHLORMETHYLISOTHIAZOLINONE
  • CMIT (5 chloro 2 Methyl 2H isothiazol-3-one
  • 5-Chloro-2-Methyl-4-isothiazolin-3-one, >14% in water.
  • CMIT/MIT-14
  • Isothiazolinones(CMI/MI)
  • ANTI-IDAS(N-TERMINAL) antibody produced in rabbit
  • IDAS
  • Multicilin
  • Protein Idas
  • 5-cloro-2-methyl-4-isothiazolin-3-one/2-methyl-2h-isothiazol-3-one
  • Isothiazolinones Solution,100ppm
  • 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (ACTIVE INGREDIENT >14%, CMI/MI 2.5 - 4.0)
  • 5-chloro-2-methyl-isothiazolylthione-3
  • kathoncg5243
  • methylchloroisothiazoline
  • 5-Chloro-2-methyl-Isothiazolone
  • 5-CHLORO-2-METHYL-ISOTHIAZOL-3-ONE
  • 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE
Description Applications Safety Information