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TOLBUTAMIDE Structure

TOLBUTAMIDE

Chemical Properties

Melting point 128-130°C
Density  1.2450
refractive index  1.6360 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Soluble in chloroform.
pka pKa 5.32(H2O t = 37) (Uncertain)
color  White to Off-White
Water Solubility  0.14g/L(25 ºC)
Merck  14,9507
BRN  1984428
Specific Activity 50-60 mCi/mmol
Concentration 0.1 mCi/ml
Solvent Ethanol
Stability Stable. Combustible.
CAS DataBase Reference 64-77-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 982XCM1FOI
ATC code A10BB03,V04CA01
NCI Drug Dictionary tolbutamide
EPA Substance Registry System Tolbutamide (64-77-7)

Safety

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H317
Precautionary statements P261-P280g-P301+P312a-P321-P333+P313-P501a
Hazard Codes  F,Xn
Risk Statements  20/21/22-40-43-36-11
Safety Statements  26-36/37/39-36/37-16-24/25
WGK Germany  2
RTECS  YS4550000
TSCA  Yes
HS Code  29350090
Hazardous Substances Data 64-77-7(Hazardous Substances Data)
Toxicity LD50 oral in rat: 2490mg/kg
NFPA 704:
1
2 0

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