Astragaloside VI
- Product NameAstragaloside VI
- CAS84687-45-6
- CBNumberCB51469395
- MFC47H78O19
- MW947.11
- MDL NumberMFCD17214426
- MOL File84687-45-6.mol
- MSDS FileSDS
Chemical Properties
Density | 1.46±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
pka | 12.89±0.70(Predicted) |
Astragaloside VI Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
ChemScene CS-0034273 | 5mg | $490 | AstragalosideVI ≥98.0% |
Buy |
Biorbyt Ltd orb572863 | 100mg | $1431.4 | Astragaloside VI |
Buy |
Biorbyt Ltd orb572863 | 250mg | $2839 | Astragaloside VI |
Buy |
Biorbyt Ltd orb572863 | 1g | $5654.2 | Astragaloside VI |
Buy |
DC Chemicals DC12126 | 1g | $3800 | AstragalosideVI >98% |
Buy |
Astragaloside VI Chemical Properties,Usage,Production
Biological Activity
Astragaloside VI accelerates wound healing by activating the epidermal growth factor receptor/extracellular signal-regulated kinase (EGFR/ERK) signaling pathway.in vitro
Pretreatment with Astragaloside VI (AS-VI) at 1 μM increases EGFR activation in HaCaT cells. Astragaloside VI, a major intestinal metabolite of astragalosides, exerts the strongest EGFR activation. In HaCaT cells, the positive control, EGF expectedly results in 1.5±0.03-fold increase in cell proliferation, compared to the control. Astragaloside VI at the indicated concentrations also significantly promots cell proliferation in both HaCaT and HDF cells. Astragaloside VI promotes neural stem cell proliferation and enhances neurological function recovery in transient cerebral ischemic injury via activating EGFR/MAPK signaling cascades.
in vivo
Astragaloside VI improves wound healing, compared to the control. In the simple noninfected wound model, wound healing in mice is accelerated by Astragaloside VI, where in the time required for wound closure is shortened by approximately 2-4 days , compared to that in the control group. Topical treatment with Astragaloside VI reduces the volume of pus produced, compared to the control group. Astragaloside VI treated wounds show an accelerated rate of healing, compared to the control and vaseline groups. By day 22, the Astragaloside VI -treated wounds fully close, whereas the blank and vaseline-treated wounds do not fully close until day 26. Angiogenesis is a crucial step in the formation of granulation tissue and wound healing. Astragaloside VI increases blood vessel formation in both the non -infected and infected wound models. Astragaloside VI could effectively activate EGFR/MAPK signaling cascades, promote NSCs proliferation and neurogenesis in transient cerebral ischemic br ains, and improve the repair of neurological functions in post-ischemic stroke rats.
target
EGFR
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Preparation Products And Raw materials
Astragaloside VI Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
+1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 | |
+86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30256 | 58 | |
+8618829768577 | gao490372054@gamil.com | China | 1250 | 58 | |
13348960310 13348960310 |
3003867561@qq.com | China | 9945 | 58 | |
021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 | |
021-36031160 13311776681 |
3338195766@QQ.com | China | 5175 | 55 | |
021-69955236-807 13918189704 |
chinaruji@chinaruji.com | China | 5176 | 55 | |
028-85370565-229 18080489829 |
3004654993@qq.com | China | 9087 | 60 | |
021-57127007-6622 15618937986 |
zhaok@nature-standard.com | China | 3920 | 58 | |
15911056312 | liming@bio-fount.com | China | 9730 | 58 |
84687-45-6, Astragaloside VIRelated Search
- Astragaloside A
- Astragaloside III
- Isoastragaloside I
- ASTRAGALOSIDE III Astragalus Saponin III Standard
- ASTRAGALOSIDE II Astragalus Saponin II Standard
- Isoastragaloside IV
- Acetytastragaloside
- ASTRAGALOSIDE I Astragalus Saponin I Standard
- AstragalosideⅠ
- neoastragaloside I
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