Description
Refer to monosodium glutamate.
Description
L-Glutamic acid is a non-essential amino acid and the primary excitatory neurotransmitter in the CNS. It acts on ionotropic and metabotropic receptors to induce excitatory synaptic transmission and has roles in synaptic plasticity. Excessive release of L-glutamic acid induces excitotoxicity that is associated with various human diseases, including amyotrophic lateral sclerosis (ALS), stroke, Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease. Excessive L-glutamic acid release, in its protonated glutamate form, also occurs during seizure activity and contributes to epileptogenesis and seizure-induced brain damage.
Uses
Monoammonium l-Glutamate is a flavor enhancer and salt substitute that is crystalline powder (white, free-flowing) and odorless. It is soluble in water, insoluble in common organic solvents, and is obtained by chemical synthesis. It is a low sodium alternative to monosodium glutamate. It is used in meats, soups, gravies, and sausage. It is also termed ammonium glutamate and monoammonium glutamate.
Uses
L-Glutamic Acid Monoammonium Salt is a food additive; It can protect hypertensive rats from strokes.
Safety Profile
Moderately toxic by
intraperitoneal route. When heated to
decomposition it emits toxic fumes
including NOx and NH3.
