ChemicalBook > CAS DataBase List > CORTISONE

CORTISONE

Product Name:
CORTISONE
CAS No.
53-06-5
Chemical Name:
CORTISONE
CBNumber:
CB6413305
Molecular Formula:
C21H28O5
Formula Weight:
360.44
MOL File:
53-06-5.mol
More
Less

CORTISONE Property

Melting point:
223-228 °C (dec.)(lit.)
alpha 
D25 +209° (c = 1.2 in 95% alcohol); 25546 +269° (c = 0.125 in benzene); 25546 +248° (c = 0.1 to 0.2 in alcohol)
Boiling point:
412.46°C (rough estimate)
Density 
1.28±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
210 ° (C=1, EtOH)
Flash point:
9℃
storage temp. 
-20°C Freezer
pka
12.37±0.60(Predicted)
Water Solubility 
229.9mg/L(25 ºC)
Merck 
2539
CAS DataBase Reference
53-06-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
F,T,Xn
Risk Statements 
11-23/24/25-39/23/24/25-63
Safety Statements 
22-24/25-45-36/37-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
RTECS 
GM9020000
18
HS Code 
2937210000
More
Less

N-Bromosuccinimide Price More Price(3)

Sigma-Aldrich Gold
Product number:
C-130
Product name :
Cortisone solution
Purity:
100 μg/mL in methanol, ampule of 1 mL, certified reference material
Packaging:
130-1ml
Price:
$51.6
Updated:
2019/12/02
Buy:
Buy
Alfa Aesar Gold
Product number:
J64182
Product name :
Cortisone
Packaging:
5g
Price:
$144
Updated:
2019/12/02
Buy:
Buy
Alfa Aesar Gold
Product number:
J64182
Product name :
Cortisone
Packaging:
1g
Price:
$44.9
Updated:
2019/12/02
Buy:
Buy
More
Less

CORTISONE Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

Glucocorticoid, anti-inflammatory agent

Uses

antiinflammatory, glucocorticoid

Uses

Anticoagulant

Definition

ChEBI: A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.

Hazard

Damaging side effects, e.g., sodium retention from ingestion.

Purification Methods

Crystallise cortisone from 95% EtOH or acetone. The UV has 14,000 M-1cm -1 at 237nm (EtOH). [Beilstein 8 IV 3480, Hems J Pharm Pharmacol 5 409 1953, Beilstein 8 IV 3480.]

CORTISONE Preparation Products And Raw materials Raw materials

Raw materials

Preparation Products

Less

CORTISONE Suppliers

Global(138)Suppliers
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Fax:
86-10-82849933
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Country:
China
ProdList:
96815
Advantage:
76
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
Tel:
0086-18858184290
Fax:
0086-571-28313105
Email:
sales@zyterpharm.com
Country:
China
ProdList:
49
Advantage:
49
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
821-50328103-801
Fax:
86-21-50328109
Email:
3bsc@sina.com
Country:
China
ProdList:
15881
Advantage:
69
Nanjing Chemlin Chemical Co., Ltd
Tel:
025-83697070
Fax:
+86-25-83453306
Email:
info@chemlin.com.cn
Country:
China
ProdList:
19992
Advantage:
64
Chemsky(shanghai)International Co.,Ltd.
Tel:
021-50135380
Email:
shchemsky@sina.com
Country:
China
ProdList:
32359
Advantage:
50
Chengdu XiYa Chemical Technology Co., Ltd.
Tel:
Fax:
028-84752058
Email:
sale@xiyashiji.com
Country:
China
ProdList:
9624
Advantage:
57
Syntechem Co.,Ltd
Tel:
Please Email
Fax:
E-Mail Inquiry
Email:
info@syntechem.com
Country:
China
ProdList:
13010
Advantage:
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel:
400 638 7771
Email:
sales@heowns.com
Country:
China
ProdList:
14460
Advantage:
57
BOC Sciences
Tel:
Email:
info@bocsci.com
Country:
United States
ProdList:
9984
Advantage:
65

53-06-5, CORTISONERelated Search:

Hydrocortisone acetate Cortisone Reductase cortisone sulfate 9-ALPHA-FLUORO-2-ALPHA-METHYL-CORTISONE 4-PREGNEN-6-ALPHA, 17,21-TRIOL-3,11,20-TRIONE CORTISONE 21-SULFATE AMMONIUM CORTISONE MESYLATE 2ALPHA-METHYLCORTISONE 16ALPHA-METHYLCORTISONE 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE CORTISONE 21-HEMISUCCINATE 4-Pregnene-17,21-diol-3,11,20-trione 21-sulphate,sodium salt CORTISONE GLUCURONIDE,CORTISONE-21BETA-GLUCURONIDE CORTISONE, [4-14C] CORTISONE, [1,2-3H] CORTISONE-21BETA-GLUCURONIDE SODIUM 4-PREGNEN-17,21-DIOL-3,11,20-TRIONE SULPHATE, TRIETHYL AMMONIUM SALT Cortisone, 21-acetate (8CI),CORTISONE-21-ACETATE, PH EUR,CORTISONE 21-ACETATE,CORTISONE ACETATE,CORTISONE ACETATE CRYSTALLINE
  • Cortandren
  • Cortisal
  • Cortisate
  • Cortison
  • Cortistal
  • Cortivite
  • Cortogen
  • delta(sup4)-pregnene-17alpha,21-diol-3,11,20-trione
  • Incortin
  • KE
  • Kendall's compound
  • Pregn-4-en-17alpha,21-diol-3,11,20-trione
  • Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-
  • Reichstein Fa
  • Scheroson
  • 4-PREGNENE-17ALPHA,21-DIOL-3,11,20-TRIONE
  • 4-PREGNEN-17ALPHA,21-DIOL-3,11,20-TRIONE
  • 4-PREGNEN-17,21-DIOL-3,11,20-TRIONE
  • 4-PREGEN-17A,21-DIOL-3,11,20-TRIONE
  • 11-DEHYDRO-17-HYDROXYCORTICOSTERONE
  • 17A 21-DIHYDROXY-4-PREGNEN-3 17 20-TRIONE
  • 17ALPHA,21-DIHYDROXYPREGN-4-ENE-3,11,20-TRIONE
  • 17ALPHA,21-DIHYDROXY-4-PREGNENE-3,11,20-TRIONE
  • 17ALPHA-HYDROXY-11-DEHYDROCORTICOSTERONE
  • 17-HYDROXY-11-DEHYDROCORTICOSTERONE
  • KENDALL'S CMPD ''E''
  • KENDALL'S ''E''
  • 4-Pregnene-17α,21-diol-3,11,20-trione
  • (8S,9S,10R,13S,14S,17R)-17-glycoloyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-quinone
  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyethanoyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
  • Cortisone-[2H7]
  • NSC 9703
  • 4-Pregnen-17a,21-diol-3,11,20-trione-d2
  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-diMethyl-7,8,9,10,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11(2H,6H)-dione
  • Cortisone solution
  • Cortisone solution,100ppm
  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyethanoyl)-10,13-dimethyl-1,2,6,7,8,9,12
  • Hydrocortisone EP Impurity B
  • 17,21-Dihydroxy-4-pregnene-3,11,20-trione
  • 17,21-Dihydroxypregn-4-ene-3,11,20-trione
  • 20-trione,17,21-dihydroxy-pregn-4-ene-11
  • Adrenalex
  • Adreson
  • Andreson
  • Corlin
  • Cortadren
  • Hydrocortisone Impurity 2(Hydrocortisone EP Impurity B)
  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,6,7,8,9,10,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-3,11(2H)-dione
  • Cortisone (17-Hydroxy-11-dehydrocorticosterone
  • KENDALL'S COMPOUND E
  • KENDALL'S COMPOUND 'E'
  • CORTONE
  • CORTISONE
  • DELTA4-PREGNENE-17, 21-DIOL-3, 11, 20-TRIONE
  • DELTA4-PREGNENE-17ALPHA,21-DIOL-3,11,20-TRIONE
  • DELTA-PREGNENE-17ALPHA,21-DIOL-3,11,20-TRIONE
  • REICHSTEIN'S SUBSTANCE FA