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Prednisone Structure

Prednisone

Chemical Properties

Melting point 236-238 °C(lit.)
alpha  169 º (c=0.5, dioxane)
Boiling point 410.86°C (rough estimate)
Density  1.1121 (rough estimate)
refractive index  170 ° (C=0.5, Dioxane)
Flash point >200℃
storage temp.  2-8°C
solubility  Practically insoluble in water, slightly soluble in ethanol (96 per cent) and in methylene chloride. It shows polymorphism (5.9).
pka 12.36±0.60(Predicted)
form  Solid
color  White to Off-White
Water Solubility  115mg/L(25 ºC)
Merck  7722
BRN  2065301
BCS Class 1?
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 53-03-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII VB0R961HZT
NCI Dictionary of Cancer Terms MOPP; prednisone
NCI Drug Dictionary prednisone
Proposition 65 List MOPP (vincristine-prednisone-nitrogen mustard-procarbazine mixture)
ATC code A07EA03,H02AB07
IARC 3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference Prednisone(53-03-2)
EPA Substance Registry System Prednisone (53-03-2)

Safety

Symbol(GHS)
Signal wordWarning
Hazard statements H373
Precautionary statements P260
Hazard Codes  Xn
Safety Statements  36/37/39-45-26-16
Hazardous Substances Data 53-03-2(Hazardous Substances Data)

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