EzetiMibe-d4
- Product NameEzetiMibe-d4
- CAS1093659-89-2
- CBNumberCB72710005
- MFC24H21F2NO3
- MW409.43
- MOL File1093659-89-2.mol
Chemical Properties
storage temp. | Store at -20°C |
solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
form | A solid |
EzetiMibe-d4 Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Cayman Chemical 25044 | 1mg | $480 | Ezetimibe-d4 ≥99% deuterated forms (d1-d4) |
Buy |
TRC E975003 | 1mg | $275 | Ezetimibe-d4 |
Buy |
AK Scientific 2934DC | 1mg | $633 | (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one |
Buy |
EzetiMibe-d4 Chemical Properties,Usage,Production
Description
Ezetimibe-d4 is intended for use as an internal standard for the quantification of ezetimibe by GC- or LC-MS. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Upon oral administration ezetimibe undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1. Ezetimibe exhibits ED50 values of 0.0005-0.05 mg/kg in various animal models, selectively blocking cholesterol absorption without inhibiting pancreatic lipolytic enzyme activities in the intestinal lumen, affecting bile acid micelle solubilization of cholesterol, or interfering with the absorption of triglycerides, fatty acids, or bile acids.Uses
Ezetimibe-d4 is the labeled analogue of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.Preparation Products And Raw materials
EzetiMibe-d4 Suppliers
Global(27)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
+1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 | |
+1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 | |
010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 | |
021-50135380 | shchemsky@sina.com | China | 32344 | 50 | |
020-81960175 | min.he@cato-chem.com | China | 1958 | 55 | |
0755-0755-66853366 13670046396 |
sales@chem-strong.com | China | 17994 | 56 | |
19138486554 18582380095 |
sales@artisbio.com | China | 2862 | 58 | |
021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 | |
028-85255396 18302801538 |
cdnovell@163.com | China | 2251 | 58 | |
+86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55896 | 58 |
1093659-89-2, EzetiMibe-d4Related Search
- Ezetimibe
- (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
- EzetiMibe Fluoro IsoMer
- EZETIMIBE PHENOXY GLUCURONIDE
- (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
- 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone
- (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid
- N,N'-Diisopropylcarbodiimide
- (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
- Ezetimibe Impurity 33
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