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8-Hydroxyquinoline Structure

8-Hydroxyquinoline

Chemical Properties

Melting point 70-73 °C(lit.)
Boiling point 267 °C752 mm Hg(lit.)
Density  1.0340
vapor pressure  0.221Pa at 25℃
refractive index  1.4500 (estimate)
Flash point 267°C
storage temp.  Store below +30°C.
solubility  0.56g/l
form  Liquid
pka 5.017(at 20℃)
color  White to pale yellow or light beige
Water Solubility  INSOLUBLE
Sensitive  Light Sensitive
Merck  14,4843
BRN  114512
InChIKey MCJGNVYPOGVAJF-UHFFFAOYSA-N
LogP 1.85 at 25℃
FDA 21 CFR 310.545
CAS DataBase Reference 148-24-3(CAS DataBase Reference)
EWG's Food Scores 1-3
FDA UNII 5UTX5635HP
ATC code A01AB07,D08AH03,G01AC30,R02AA14
IARC 3 (Vol. 13, Sup 7) 1987
NIST Chemistry Reference 8-Quinolinol(148-24-3)
EPA Substance Registry System 8-Quinolinol (148-24-3)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H301-H317-H318-H360D-H410
Precautionary statements P202-P273-P280-P301+P310-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-68-36/37/38
Safety Statements  45-36/37/39-26-36
RIDADR  2811
WGK Germany  3
RTECS  VC4200000
Hazard Note  Harmful/Irritant
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29334990
Hazardous Substances Data 148-24-3(Hazardous Substances Data)
Toxicity An LD50 value of 1,200mg/kg was reported for oral administration of 8-hydroxyquinoline to rats (straidsex unspecified; AAPCO, 1966);a value of 48 mg/kg was reported for intraperitoneal administration to mice (strain/sex unspecxed; Bernstein et al., 1963).
NFPA 704:
1
2 0

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