ChemicalBook > CAS DataBase List > DROPERIDOL

DROPERIDOL

Product Name:
DROPERIDOL
CAS No.
548-73-2
Chemical Name:
DROPERIDOL
CBNumber:
CB9145418
Molecular Formula:
C22H22FN3O2
Formula Weight:
379.43
MOL File:
548-73-2.mol
More
Less

DROPERIDOL Property

Melting point:
148-149°C
Density 
1.2154 (estimate)
storage temp. 
2-8°C
solubility 
Practically insoluble in water, freely soluble in dimethylformamide and in methylene chloride, sparingly soluble in ethanol (96 per cent).
pka
7.64(at 25℃)
form 
neat
Water Solubility 
4.1mg/L(30 ºC)
CAS DataBase Reference
548-73-2(CAS DataBase Reference)
EPA Substance Registry System
2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro- (548-73-2)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
RIDADR 
3249
WGK Germany 
3
RTECS 
DE2100000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933995800
Toxicity
LD50 oral in rat: 750mg/kg
More
Less

N-Bromosuccinimide Price More Price(7)

Sigma-Aldrich Gold
Product number:
D1414
Product name :
Droperidol
Packaging:
1g
Price:
$121
Updated:
2019/12/02
Buy:
Buy
Sigma-Aldrich Gold
Product number:
1229001
Product name :
Droperidol
Purity:
United States Pharmacopeia (USP) Reference Standard
Packaging:
250mg
Price:
$352.8
Updated:
2019/12/02
Buy:
Buy
Cayman Chemical Gold
Product number:
18884
Product name :
Droperidol
Purity:
≥98%
Packaging:
1g
Price:
$90
Updated:
2020/06/24
Buy:
Buy
Cayman Chemical Gold
Product number:
18884
Product name :
Droperidol
Purity:
≥98%
Packaging:
50mg
Price:
$25
Updated:
2020/06/24
Buy:
Buy
Sigma-Aldrich Gold
Product number:
D3100000
Product name :
Droperidol
Purity:
European Pharmacopoeia (EP) Reference Standard
Packaging:
d3100000
Price:
$183
Updated:
2019/12/02
Buy:
Buy
More
Less

DROPERIDOL Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

H2 antihistamine

Uses

A D1DR and D2DR inhibitor.

Uses

A D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.

Definition

ChEBI: An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeo .

brand name

Inapsine (Akorn);Dehydrobenzperidol;Diaperidol;Inopsin.

General Description

Droperidol, 1-{1-[3-(p-fluorobenzoyl)propyl]-1,2, 3,6-tetrahydro-4-pyridyl}-2-benzimidazolinone(Inapsine), may be used alone as a preanestheticneuroleptic or as an antiemetic. Because of its very shortactingand highly sedating properties, its most frequent useis in combination (Innovar) with the narcotic agent fentanyl(Sublimaze) preanesthetically.

General Description

Droperidol, 1-1-[3-(p-fluorobenzoyl)propyl]-1,2,[3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone(Inapsine). Centrally acting acetylcholinesteraseinhibitors may increase the risk of antipsychotic-relatedEPS. CNS depressants may produce additive sedativeeffects (benzodiazepines, barbiturates, antipsychotics,ethanol, opiates, and other sedative medications).Droperidol in combination with certain forms of inhalationanesthetics may produce peripheral vasodilatation and hypotension.Metoclopramide may increase the risk of EPSproduced by droperidol.

Less

DROPERIDOL Suppliers

Global(123)Suppliers
Zhongxiang Yaowei Biological Technology Co., Ltd.
Tel:
153-37241005- ;
Email:
w13260682861@163.com;516219607@qq.com
Country:
China
ProdList:
1869
Advantage:
58
Shanghai Boyle Chemical Co., Ltd.
Fax:
86-21-57758967
Email:
sales@boylechem.com
Country:
China
ProdList:
2926
Advantage:
55
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Fax:
86-10-82849933
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Country:
China
ProdList:
96815
Advantage:
76
Nanjing Chemlin Chemical Co., Ltd
Tel:
025-83697070
Fax:
+86-25-83453306
Email:
info@chemlin.com.cn
Country:
China
ProdList:
19991
Advantage:
64
Chemsky(shanghai)International Co.,Ltd.
Tel:
021-50135380
Email:
shchemsky@sina.com
Country:
China
ProdList:
32358
Advantage:
50
Syntechem Co.,Ltd
Tel:
Please Email
Fax:
E-Mail Inquiry
Email:
info@syntechem.com
Country:
China
ProdList:
13010
Advantage:
57
Sinopharm Chemical Reagent Co,Ltd.
Tel:
86-21-63210123
Fax:
86-21-63290778 86-21-63218885
Email:
sj_scrc@sinopharm.com
Country:
China
ProdList:
9848
Advantage:
79
Dalian Meilun Biotech Co., Ltd.
Tel:
0411-66771943- ;0411-66771942
Fax:
0411-66771945
Email:
sales@meilune.com;sales@meilune.com;
Country:
China
ProdList:
3941
Advantage:
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel:
17727448752,0755-83725681-603
Fax:
+86 755 28094224
Email:
rex.liu@phystandard.com;tom.liu@phystandard.com
Country:
China
ProdList:
4508
Advantage:
50

548-73-2, DROPERIDOLRelated Search:

EPZ004777 Saracatinib Zoledronic acid 3-Aminobenzamide Olaparib Calcitriol 1-EBIO 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE 4-(4-FLUOROPHENYL)BUTAN-1-AMINE 1-(4-FLUORO-PHENYL)-BUTAN-1-ONE N1-(3-(DIMETHYLAMINO)PROPYL)BENZENE-1,2-DIAMINE 2-Hydroxybenzimidazole DROPERIDOL 4'-Fluoropropiophenone 1-METHYL-2-BENZIMIDAZOLINONE 5-Diethylamino-2-pentanone 1,3-DIHYDRO-1-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-2H-BENZIMIDAZOLE-2-ONE
  • Deidrobenzperidolo
  • Dihidrobenzperidol
  • Dridol
  • Droleptan
  • Halkan
  • Inappin
  • Inapsin
  • Inapsine
  • Innovan
  • Innovar
  • Innovar-Vet
  • Inopsin
  • Inoval
  • Leptanal
  • Leptofen
  • McN-JR 4749
  • mcn-jr4749
  • mcn-jr-4749
  • Properidol
  • R 4749
  • r4749
  • Sintodril
  • Sintosian
  • Thalamanol
  • Thalamonal
  • Vetkalm
  • DROPERIDOL
  • 1-(1-[4-FLUOROBENZOYLPROPYL]-1,2,3,6-TETRAHYDRO-4-PYRIDYL)-2-BENZIMIDAZOLINONE
  • 1-[1-(P-FLUOROBENZOYLPROPYL)-1,2,3,6-TETRAHYDRO-4-PYRIDYL]-2-BENZIMIDAZOLINONE
  • 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazo
  • 1-(1-(3-(p-Fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
  • 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-2h-benzimidazol-2-on
  • 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimi
  • 1-(1-(4-(p-Fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
  • 1-(1-(4-(p-fluorophenyl-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidaz
  • 1-(4-Fluorophenyl)-4-(4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl)-1-butanone
  • 1-{1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl}-2-benzimidazolinone
  • 2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-
  • 2-benzimidazolinone,1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyri
  • 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-
  • 3-dihydro-4-pyridinyl)-
  • component of Innovar
  • component of Thalamonal
  • Dehidrobenzperidol
  • Dehydrobenzperidol
  • 3-(1-(3-(4-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-1H-benzimidazol-2-one
  • DROPERIDOL,USP
  • 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one
  • Neurolidol
  • NSC 169874
  • R 474
  • 1-[1-[4-(p-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl]-2,3-dihydro-1H-benzimidazol-2-one
  • 3-[1-[4-(4-fluorophenyl)-4-keto-butyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-benzimidazol-2-one
  • 3-[1-[4-(4-fluorophenyl)-4-oxo-butyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-benzimidazol-2-one
  • 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-benzimidazol-2-one
  • Droperidol,1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone
  • Droperidol (250 mg)
  • 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]iMidazol-2(3H)-one