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Pioglitazone

Product Name:
Pioglitazone
CAS No.
111025-46-8
Chemical Name:
Pioglitazone
CBNumber:
CB9257580
Molecular Formula:
C19H20N2O3S
Formula Weight:
356.44
MOL File:
111025-46-8.mol
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Pioglitazone Property

Melting point:
183-184 C
Boiling point:
575.4±45.0 °C(Predicted)
Density 
1.260±0.06 g/cm3(Predicted)
form 
White to off-white solid.
pka
6.35±0.50(Predicted)
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Safety

Hazard Codes 
F,C
Risk Statements 
11-34
Safety Statements 
16-26-36/37/39-45
Hazardous Substances Data
111025-46-8(Hazardous Substances Data)
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N-Bromosuccinimide Price More Price(4)

Cayman Chemical Gold
Product number:
71745
Product name :
Pioglitazone
Purity:
≥98%
Packaging:
1mg
Price:
$17
Updated:
2018/11/13
Buy:
Buy
Cayman Chemical Gold
Product number:
71745
Product name :
Pioglitazone
Purity:
≥98%
Packaging:
5mg
Price:
$30
Updated:
2018/11/13
Buy:
Buy
Cayman Chemical Gold
Product number:
71745
Product name :
Pioglitazone
Purity:
≥98%
Packaging:
25mg
Price:
$68
Updated:
2018/11/13
Buy:
Buy
Cayman Chemical Gold
Product number:
71745
Product name :
Pioglitazone
Purity:
≥98%
Packaging:
50mg
Price:
$119
Updated:
2018/11/13
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Buy
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Pioglitazone Chemical Properties,Usage,Production

Uses

antihyperlipidemic, HMGCoA reductase inhibitor

Definition

ChEBI: A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic acti ity.

Indications

Pioglitazone is approved for use as monotherapy and in conjunction with metformin, sulfonylureas, and insulin. It is taken once a day with or without food. Though pioglitazone may also cause a small increase in low-density lipoprotein concentrations, there is usually a modest decrease in triglyceride levels, but it unclear whether this has any clinical significance or persists in the long term.

brand name

Actos (Takeda).

General Description

Pioglitazone, (±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione (Actos),is an odorless, white, crystalline powder that must be convertedto a salt such as its hydrochloride before it will haveany water solubility. Although the molecule contains one chiralcenter, the compound is used as the racemic mixture. Thisis primarily a result of the in vivo interconversion of the twoenantiomers. Thus, there are no differences in the pharmacologicalactivity of the two enantiomers.

Pioglitazone Preparation Products And Raw materials Raw materials

Raw materials

Preparation Products

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Pioglitazone Suppliers

Global(170)Suppliers
Shanghai ACT chemical Limited
Tel:
21-59904146-
Fax:
+86-21-59904146
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sales@actchemical.com
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China
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496
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J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Fax:
86-10-82849933
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Country:
China
ProdList:
96815
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76
Pure Chemistry Scientific Inc.
Tel:
001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
Email:
sales@chemreagents.com
Country:
United States
ProdList:
9919
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62
LGM Pharma
Tel:
1-(800)-881-8210
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615-250-9817
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inquiries@lgmpharma.com
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United States
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1940
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70
Nanjing Chemlin Chemical Co., Ltd
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025-83697070
Fax:
+86-25-83453306
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info@chemlin.com.cn
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China
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19986
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XiaoGan ShenYuan ChemPharm co,ltd
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0712-2580635- ;0712-2580635
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Beijing Isomersyn Technology CO;LTD
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China Langchem Inc.
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021-58956006- ;021-58950017-
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
Email:
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Country:
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111025-46-8, PioglitazoneRelated Search:

PINEPOLLEN 5-Hydroxy Pioglitazone EPEBT(INTERMEDIATE OF PIOGLITAZONE HCL) 5-Desethyl 5-Carboxy Pioglitazone Pioglitazone N-Oxide Hydroxy Pioglitazone-D5 (Major) (M-IV) (Mixture of diastereomers) N-Hydroxy Pioglitazone-deuterated (M-IV) (Mixture of diastereomers) 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione N-[Ethyl-(2-pyridyl-5-ethyl) Pioglitazone(Pioglitazone Impurity),4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester(Pioglitazone Impurity) PIOGLITAZONE-D3 PIOGLITAZONE-D4, KETONE Pioglitazone, hydroxyl M-II,Hydroxy Pioglitazone (M-II) (Mixture of Diastereomers) 5-[4-[2-(5-ETHYL-2-PYRIDYL) ETHOXY] BENZYL}-2-IMINO-4-THIAZOLIDINONE, PIOGLITAZONE INETRMEDIATE PG-4 4-METHOXYTOLUENE-2,3,5,6-D4 5-Ethyl-2-pyridineethanol Keto Pioglitazone Discontinued see product # K200600,Keto Pioglitazone,Keto-Pioglitazone (M-III),Pioglitazone, ketone Pioglitazone Pioglitazone, hydroxy M-IV,Hydroxy Pioglitazone (M-IV)
  • 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione
  • Pioglitazone (Actos)
  • 2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-
  • Pioglitazone 5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
  • 5-[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL-2,4-THIAZOLIDINEDIONE
  • 5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE
  • 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
  • Pioglitazone free base
  • Pioglitazone and its intermeidates
  • Pioglitazone
  • PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL)
  • PINEPOLLEN
  • 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione
  • (5S)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione
  • U 72107
  • 111025-46-8
  • C19H20N2O3S
  • APIS
  • LESCOL