Azido-PEG3-Maleimide
- Product NameAzido-PEG3-Maleimide
- CAS1858264-36-4
- CBNumberCB93162867
- MFC15H23N5O6
- MW369.37302
- MDL NumberMFCD22380764
- MOL File1858264-36-4.mol
Azido-PEG3-Maleimide Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Chem-Impex 35111 | 5MG | $67.2 | Azido-PEG3-maleimide |
Buy |
| BroadPharm BP-22468 | 25mg | $95 | Azido-PEG3-Maleimide 95% |
Buy |
| Chem-Impex 35111 | 25MG | $123.2 | Azido-PEG3-maleimide |
Buy |
| ChemScene CS-0114354 | 25mg | $165 | Azido-PEG3-maleimide |
Buy |
| BroadPharm BP-22468 | 100mg | $195 | Azido-PEG3-Maleimide 95% |
Buy |
Azido-PEG3-Maleimide Chemical Properties,Usage,Production
Description
Azido-PEG3-Maleimide is provided as a kit of two vials. Azido-PEG3-Maleimide is not stable for storage; it needs to be made in situ by mixing Azido-PEG3-amine and Maleimide-NHS ester followed by shaking/ stirring for 30 minutes at room temperature. The maleimide group of the Azido-PEG3-Maleimide can react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Azide group enables Click Chemsitry reactions.Biological Activity
Azido-PEG3-maleimide is a PROTAC linker belonging to the PEG class, which can be used to synthesize PROTAC molecules. Azido-PEG3-maleimide is also a cleavable ADC linker containing 3-unit PEG, which can be used to synthesize antibody drug conjugates (ADCs).in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| PEGs
| Cleavable
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 | |
| +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 | |
| 571-86758373 +8613588754946 |
sales@huarongpharm.com | CHINA | 3149 | 58 | |
| +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19915 | 58 | |
| +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 | |
| +undefined18143011203 | info@chemextension.com | China | 42057 | 58 | |
| +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 | |
| 19916721580 | mafarm@126.com | China | 4115 | 58 | |
| 0431-80514535 19917294565 |
et@chemextension.com | China | 4108 | 55 | |
| 13006575422@163.com | China | 6357 | 58 |
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