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Methyl cyanoacetate

Product Name:
Methyl cyanoacetate
CAS No.
105-34-0
Chemical Name:
Methyl cyanoacetate
CBNumber:
CB9485583
Molecular Formula:
C4H5NO2
Formula Weight:
99.09
MOL File:
105-34-0.mol
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Methyl cyanoacetate Property

Melting point:
-13 °C
Boiling point:
204-207 °C(lit.)
Density 
1.123 g/mL at 25 °C(lit.)
vapor density 
3.41 (vs air)
vapor pressure 
0.2 mm Hg ( 20 °C)
refractive index 
n20/D 1.417(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
54g/l
pka
2.75±0.10(Predicted)
form 
Liquid
color 
Clear colorless to very slightly yellow
Water Solubility 
54 g/L (20 ºC)
Sensitive 
Light Sensitive
BRN 
773945
CAS DataBase Reference
105-34-0(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, cyano-, methyl ester(105-34-0)
EPA Substance Registry System
Acetic acid, cyano-, methyl ester (105-34-0)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
RIDADR 
3276
WGK Germany 
1
RTECS 
AG4375000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29269095
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N-Bromosuccinimide Price More Price(8)

Sigma-Aldrich Gold
Product number:
108421
Product name :
Methyl cyanoacetate
Purity:
99%
Packaging:
25g
Price:
$37.3
Updated:
2021/03/22
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Buy
Sigma-Aldrich Gold
Product number:
108421
Product name :
Methyl cyanoacetate
Purity:
99%
Packaging:
2kg
Price:
$180
Updated:
2021/03/22
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Buy
TCI Chemical Gold
Product number:
C0442
Product name :
Methyl Cyanoacetate
Purity:
>99.0%(GC)
Packaging:
25mL
Price:
$24
Updated:
2021/03/22
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Buy
TCI Chemical Gold
Product number:
C0442
Product name :
Methyl Cyanoacetate
Purity:
>99.0%(GC)
Packaging:
500mL
Price:
$53
Updated:
2021/03/22
Buy:
Buy
Alfa Aesar Gold
Product number:
A15555
Product name :
Methyl cyanoacetate, 99%
Packaging:
500g
Price:
$54.8
Updated:
2021/03/22
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Buy
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Methyl cyanoacetate Chemical Properties,Usage,Production

Description

Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds. It is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate; a compound used in the synthesis of DPP-IV inhibitors for treating type-2 diabetes. In addition, it is an intermediate in the preparation of α-cyanoacrylate, malononitrile, and 1,1-cyclohexanediacetic acid dyes. It is used as UV absorber or stabilizer, intermediate for pharmaceuticals. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds.

Chemical Properties

clear colorless to very slighlty yellow liquid

Uses

pharmaceutical intermediate

Purification Methods

Purify the ester by shaking with 10% Na2CO3 solution, wash well with water, dry with anhydrous Na2SO4, and distil it. [Beilstein 2 H 584, 2 I 253, 2 II 530, 2 III 1628, 2 IV 1889.]

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Methyl cyanoacetate Suppliers

Global(333)Suppliers
Nanjing Apicci Pharmaceutical Technology Co., Ltd.
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Creasyn Finechem(Tianjin) Co., Ltd.
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022-83945878-
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022-83945176
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J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Fax:
86-10-82849933
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jkinfo@jkchemical.com;market6@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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21-61259100-
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86-21-61259102
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sh@meryer.com
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future industrial shanghai co., ltd
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Alfa Aesar
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021-67582001/03/05
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TCI (Shanghai) Development Co., Ltd.
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021-67121386 / 800-988-0390
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Sales-CN@TCIchemicals.com
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ShangHai DEMO Chemical Co.,Ltd
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Beijing dtftchem Technology Co., Ltd.
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86 (10) 60270825
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105-34-0, Methyl cyanoacetateRelated Search:

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Description