5,25R-Cholesten-3beta,26-diol

Basic information Safety Related Supplier

5,25R-Cholesten-3beta,26-diol Basic information

Product Name:
5,25R-Cholesten-3beta,26-diol
CAS:
20380-11-4
MF:
C27H46O2
MW:
402.65
Mol File:
20380-11-4.mol
More
Less

5,25R-Cholesten-3beta,26-diol Chemical Properties

Melting point:
172-174 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6))
Boiling point:
517.1±23.0 °C(Predicted)
Density 
1.03
form 
White solid.
pka
15.03±0.70(Predicted)
More
Less

5,25R-Cholesten-3beta,26-diol Usage And Synthesis

Uses

The liver x receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. 25(R)-27-hydroxy Cholesterol is the more predominant-occurring (~80%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol.[Cayman Chemical]

Definition

ChEBI: A 26-hydroxycholesterol in which the 25-position has R-configuration.

More
Less

5,25R-Cholesten-3beta,26-diolSupplierMore

MedChemexpress LLC Gold
Tel:
609-228-6898
Email:
sales@medchemexpress.com
ShangHai YuanYe Biotechnology Co., Ltd.
Tel:
021-61312847-
Email:
2797782341@qq.com
Chengdu Biopurify Phytochemicals Ltd.
Tel:
028-82633397
Email:
sales03@biopurify.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel:
021-20337333-801
Email:
market@aladdin-e.com
ChemStrong Scientific Co.,Ltd
Tel:
0755-66853366-
Email:
sales@chem-strong.com
Basic information Safety Related Supplier