ChemicalBook >  Product Catalog >  Biochemical Engineering >  Condensing agent >  1,1'-Carbonyldiimidazole

1,1'-Carbonyldiimidazole

Basic information Safety Related Supplier

1,1'-Carbonyldiimidazole Basic information

Product Name:
1,1'-Carbonyldiimidazole
CAS:
530-62-1
MF:
C7H6N4O
MW:
162.15
EINECS:
208-488-9
Mol File:
530-62-1.mol
More
Less

1,1'-Carbonyldiimidazole Chemical Properties

Melting point:
117-122 °C(lit.)
Boiling point:
288.83°C (rough estimate)
Density 
1.303 g/mL at 25 °C
refractive index 
n20/D1.434
storage temp. 
2-8°C
solubility 
Soluble in dimethylformamide.
pka
2.90±0.10(Predicted)
form 
Crystalline Powder
color 
White to light cream
PH
7.7 (50g/l, H2O, 20℃)
PH Range
7.7 at 50 g/l
Water Solubility 
Insoluble in water
Sensitive 
Moisture Sensitive
Merck 
14,1819
BRN 
6826
Stability:
Stable, but moisture-sensitive. Incompatible with acids, strong oxidizing agents, water.
InChIKey
PFKFTWBEEFSNDU-UHFFFAOYSA-N
CAS DataBase Reference
530-62-1(CAS DataBase Reference)
EPA Substance Registry System
1H-Imidazole, 1,1'-carbonylbis- (530-62-1)
More
Less

Safety Information

Hazard Codes 
C,Xi,Xn
Risk Statements 
22-34-36/37/38-40-36/38
Safety Statements 
26-36/37/39-45-37/39-27-36/37
RIDADR 
UN 3263 8/PG 2
WGK Germany 
2
10-21
Hazard Note 
Harmful/Corrosive/Moisture Sensitive
TSCA 
T
HazardClass 
8
PackingGroup 
III
HS Code 
29332990
Toxicity
LD50 orally in Rabbit: 1071 mg/kg

MSDS

More
Less

1,1'-Carbonyldiimidazole Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

Used in the synthesis of peptides. Contains up to 10% imidazole.

Uses

peptide coupling reagent

Uses

CDI is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates.

Uses

1,1'-Carbonyldiimidazole is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.

Purification Methods

Crystallise it from *benzene or tetrahydrofuran in a dry-box and store it dry. [Hearn Methods Enzymol 135 102 1987, Beilstein 23/4 V 245.]

More
Less

1,1'-CarbonyldiimidazoleSupplierMore

Linhai kaile chemical plant Gold
Tel:
Email:
caixm@kailechem.com
Suzhou NMT Biotech Co., Ltd. Gold
Tel:
0512-62388427
Email:
longchengnmt@gmail.com;longchengnmt@gmail.com
Shanghai Medpep Co., Ltd Gold
Tel:
021-65566949
Email:
sales@medpep.com
Wuhan Heshun Technology Co., Ltd. Gold
Tel:
Email:
1491643168@qq.com
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. Gold
Tel:
0513-81283365-
Email:
sales4@btcpharm.com
Basic information Safety Related Supplier