Basic information Application in Ischemic Stroke Description References Safety Related Supplier
Warfarin Structure

Warfarin

Chemical Properties

Melting point 162-164 °C(lit.)
Boiling point 356°C
Density  1.1411 (rough estimate)
vapor pressure  0.09 at 22 °C (NIOSH, 1997)
refractive index  1.4434 (estimate)
Flash point 2℃
storage temp.  2-8°C
solubility  Soluble in benzene, 1,4-dioxane (Weast, 1986), and acetone (Sax and Lewis, 1987). Moderately soluble in methanol, ethanol, isopropanol, and some oils (Windholz et al., 1983). Also soluble in toluene.
form  Crystalline
pka pKa 4.90±0.01(H2O t = 25±0.5 I = 0.15 (KCl))(Approximate)
color  Colorless
Odor odorless
Water Solubility  Practically insoluble
Merck  13,10097
BRN  8868198
Exposure limits NIOSH REL: TWA 0.1 mg/m3, IDLH 100 mg/m3; OSHA PEL: 0.1 mg/m3; ACGIH TLV: TWA 0.1 mg/m3.
LogP 2.600
CAS DataBase Reference 81-81-2(CAS DataBase Reference)
NIST Chemistry Reference 3-(Alpha-acetonylbenzyl)-4-hydroxycoumarin(81-81-2)
EPA Substance Registry System Warfarin (81-81-2)

Safety Information

Hazard Codes  T,T+,Xn,F
Risk Statements  61-48/25-52/53-28-21-36-20/21/22-11
Safety Statements  53-45-61-52-36/37-28-26-16
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  GN4550000
HazardClass  6.1(a)
PackingGroup  I
HS Code  29322090
Hazardous Substances Data 81-81-2(Hazardous Substances Data)
Toxicity EC50 (24-hour) for Daphnia magna 88.8 mg/L (Lilius et al., 1995); acute oral LD50 for rats 186 mg/kg (Hartley and Kidd, 1987), 3 mg/kg (RTECS, 1985)
IDLA 100 mg/m3

MSDS

Usage And Synthesis

Warfarin Supplier

Warfarin manufacturers