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Iodotrimethylsilane

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Iodotrimethylsilane Basic information

Product Name:
Iodotrimethylsilane
CAS:
16029-98-4
MF:
C3H9ISi
MW:
200.09
EINECS:
240-171-0
Mol File:
16029-98-4.mol
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Iodotrimethylsilane Chemical Properties

Melting point:
<0°C
Boiling point:
106 °C(lit.)
Density 
1.406 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.471(lit.)
Flash point:
−25 °F
storage temp. 
−20°C
solubility 
reacts
form 
Liquid
color 
Clear colorless to reddish
Specific Gravity
1.47
Water Solubility 
reacts
Sensitive 
Moisture & Light Sensitive
BRN 
1731136
InChIKey
CSRZQMIRAZTJOY-UHFFFAOYSA-N
CAS DataBase Reference
16029-98-4(CAS DataBase Reference)
NIST Chemistry Reference
Iodotrimethylsilane(16029-98-4)
EPA Substance Registry System
Silane, iodotrimethyl- (16029-98-4)
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Safety Information

Hazard Codes 
F,C
Risk Statements 
11-14-34
Safety Statements 
16-26-36/37/39-43-45-25
RIDADR 
UN 2924 3/PG 2
WGK Germany 
3
8-21
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29310095

MSDS

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Iodotrimethylsilane Usage And Synthesis

Uses

Trimethylsilyliodide is a typical blocking agent in pharmaceutical manufacturing, widely used in the syntheses of drugs. It can protect or deprotect functional groups selectively, act as silane blocking agent.

Chemical Properties

Straw liquid

Uses

Iodotrimethylsilane is an efficient reagent for ether, ester, carbamate, ketal, and lactone cleavage.

Reactions

Trimethylsilyl iodide reacts under mild conditions in the absence of a catalyst with alkyl fluorides as well as with benzyl and tertiary alkyl chlorides and bromides to give good yields of alkyl iodides and the corresponding trimethylsilyl halides.

Purification Methods

Add a little antimony powder and fractionate with this powder in the still. 20 1.470. Stabilise the distillate with 1% wt of Cu powder. [Eaborn J Chem Soc 3077 1950, Beilstein 4 IV 4009.]

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IodotrimethylsilaneSupplierMore

Yangzhou Upkind Technologies Co. Ltd. Gold
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+86-514-85083570
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upkind@upkind.com
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. Gold
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021-52696680
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bangchem1@163.com
Shanghai Darui Fine Chemicals Co., Ltd. Gold
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021-33922791-0
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ShangHai Zexin Chemical Technology Co., Ltd. Gold
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15901897992,13052395209,021-60136491
Email:
jianglijuan101@163.com,sales@zexinchem.cn
TCI AMERICA Gold
Tel:
+1-800-423-8616 / +1-503-283-1681
Email:
sales@tciamerica.com
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