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Dehydrocholic acid

Basic information Description References Safety Related Supplier

Dehydrocholic acid Basic information

Product Name:
Dehydrocholic acid
CAS:
81-23-2
MF:
C24H34O5
MW:
402.52
EINECS:
201-335-7
Mol File:
81-23-2.mol
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Dehydrocholic acid Chemical Properties

Melting point:
238-240 °C
alpha 
29 º (c=2, dioxane)
Boiling point:
444.65°C (rough estimate)
Density 
1.0687 (rough estimate)
refractive index 
30.5 ° (C=2, Dioxane)
solubility 
ethanol: 10 mg/mL
pka
pKa 5.12(H2O t = 20 c > CMC) (Uncertain)
Water Solubility 
65mg/L(30 ºC)
Merck 
14,2868
BRN 
3226734
CAS DataBase Reference
81-23-2(CAS DataBase Reference)
NIST Chemistry Reference
Dehydrocholic acid(81-23-2)
EPA Substance Registry System
Cholan-24-oic acid, 3,7,12-trioxo-, (5.beta.)- (81-23-2)
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Safety Information

Safety Statements 
24/25
WGK Germany 
2
RTECS 
FZ2300000
TSCA 
Yes
HS Code 
2918300000

MSDS

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Dehydrocholic acid Usage And Synthesis

Description

Dehydrocholic acid is a semisynthetic bile acid, which is made by the oxidation of cholic acid by chromic acid. It can increase the output of bile by the liver and the filling of the gallbladder. Dehydrocholic acid aids the digestion of fats and increases absorption of fat soluble vitamins.
It is used as a gastrointestinal agent that stimulates the flow of bile into the duodenum (cholagogue) or stimulate the production of bile by the liver (choleretic). It is also used as laxative to relief constipation, diuretic, and a diagnostic aid.

References

[1] Giancarlo Cravotto, Arianna Binello, Luisa Boffa, Ornelio Rosati, Marco Boccalini, Stefano Chimichi (2006) Regio- and stereoselective reductions of dehydrocholic acid, Steroids, 469-475
[2] https://pubchem.ncbi.nlm.nih.gov/compound/dehydrocholic_acid

Chemical Properties

white to off-white amorphous powder

Uses

choleretic

Uses

antibacterial

brand name

Decholin Sodium (Bayer).

Dehydrocholic acid Preparation Products And Raw materials

Raw materials

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Dehydrocholic acidSupplierMore

J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
821-50328103-801
Email:
3bsc@sina.com
Alfa Aesar
Tel:
400-610-6006; 021-67582000
Email:
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
Basic information Description References Safety Related Supplier