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Isosorbide

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Isosorbide Basic information

Product Name:
Isosorbide
CAS:
652-67-5
MF:
C6H10O4
MW:
146.14
EINECS:
211-492-3
Mol File:
652-67-5.mol
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Isosorbide Chemical Properties

Melting point:
60-63 °C(lit.)
alpha 
42 º (c=3, H2O)
Boiling point:
175°C/2mmHg(lit.)
Density 
1.0945 (rough estimate)
refractive index 
45 ° (C=5, H2O)
storage temp. 
Refrigerator
form 
Crystals, Crystalline Solid or Mass
pka
13.17±0.40(Predicted)
color 
Off-white to light yellow or beige
optical activity
[α]20/D +45.2°, c = 3 in H2O
Water Solubility 
Soluble in alcohols, water and ketones.
Sensitive 
Hygroscopic
Merck 
14,5224
BRN 
80510
InChIKey
KLDXJTOLSGUMSJ-JGWLITMVSA-N
CAS DataBase Reference
652-67-5(CAS DataBase Reference)
EPA Substance Registry System
D-Glucitol, 1,4:3,6-dianhydro- (652-67-5)
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Safety Information

Risk Statements 
22
Safety Statements 
24/25
WGK Germany 
2
RTECS 
LZ4380000
TSCA 
Yes
HS Code 
29349990
Hazardous Substances Data
652-67-5(Hazardous Substances Data)

MSDS

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Isosorbide Usage And Synthesis

Chemical Properties

off-white to light yellow or beige crystals,

Uses

Isosorbide is a reagent widely used to prepare detergents, cleansers, cosmetics, agrochemicals and vasodilators.

Uses

pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives; the nitrate esters find use as vasodilators and coronary disease therapeutics.

Definition

A polyol with a hydroxyl group attached to each of two cis-oriented saturated furan rings. Intermediate for pharmaceuticals. Combustible.

brand name

Ismotic (Alcon).

Biological Functions

emergency treatment of acute angle-closure glaucoma. It should not be confused with isosorbide dinitrate, an antianginal drug.

Isosorbide Preparation Products And Raw materials

Raw materials

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IsosorbideSupplierMore

Jinan Hongbaifeng Industry And Trade Co., Ltd. Gold
Tel:
0531-87333789;0531-87333789
Email:
hongbaifeng@live.cn;hongbaifeng@live.cn
Yantai Shunkang Biotechnology Co., Ltd. Gold
Tel:
0535-7876627-
Email:
shunkang@ytsk.com.cn;
Wuxi Jingyao Bio-Technology Co., Ltd. Gold
Tel:
510-88770633-
Email:
jingyaobiotech@126.com;
Foshan DaoQi Biological Co., Ltd. Gold
Tel:
Email:
2355880548@qq.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
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