DINITROTOLUENE Usage And Synthesis
In the production of toluene diisocyanate, which is, in turn, used to produce polyurethane foams; explosives; dyes
A yellow crystalline solid or an oily liquid consisting of the three isomers. Insoluble in water and denser than water. Produces toxic oxides of nitrogen during combustion. Toxic by skin absorption, ingestion or inhalation.
Air & Water Reactions
Insoluble in water.
DINITROTOLUENE is incompatible with strong oxidizing agents, caustics, active metals, tin and zinc . Decomposes at 250°C. Prolonged heating below this temperature causes some decomposition, and the presence of impurities may decrease the decomposition temperatures. Decomposition is self-sustaining at 280°C. Containers may explode in a fire [USCG, 1999]. Reacts with oxidizing agents, caustics, nitric acid, reducing materials and metals such as zinc or tin. May react violently in the presence of a base or when heated to the boiling point. Attacks some forms of plastics, rubbers and coatings. .
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Combustible material: may burn but does not ignite readily. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Confirmed carcinogen with experimental tumorigenic and teratogenic data. A poison. Experimental reproductive effects. Mutation data reported. Flammable. When heated to decomposition it emits toxic fumes of NOx. See also 2,4-DINITROTOLUENE
The DNTs appear to cause mutations in
Salmonella typhimurium assays after metabolic
activation.12 In vivo 2,4-DNT causes unscheduled
DNA synthesis in rat hepatocytes and
chromosomal aberrations in human lymphocytes;
both 2,4- and 2,6-DNT have induced
DNA adducts in rat liver.
All six isomers have been found to be nonirritating in the eye of rabbits. Applied to the skin of rabbits, 2,4-, 2,6-, and 3,5-DNT were nonirritating whereas 2,3-, 3,4-, and 2,5-DNT were mildly to moderately irritating.1 The 2003 ACGIH threshold limit valuetime- weighted average (TLV-TWA) for dinitrotoluene is 0.2mg/m3 (0.03ppm) with an A3-confirmed animal carcinogen with unknown relevance to humans designation and a notation for skin absorption.
DINITROTOLUENE Preparation Products And Raw materials
- TERT-BUTYL ISOCYANIDE
- METHYL ISOCYANOACETATE
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- COBALT ETHYLENE DIAMINE CHLORIDE
- COBALT(II) ACETYLACETONATE
- Tosylmethyl isocyanide
- BENZYL ISOCYANIDE
- Ethyl isocyanoacetate
- Ferric acetylacetonate
- Cupric acetylacetonate
- 2,4-PENTANEDIONE, SILVER DERIVATIVE
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