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GO 6976

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GO 6976 Basic information

Product Name:
GO 6976
CAS:
136194-77-9
MF:
C24H18N4O
MW:
378.43
EINECS:
200-258-5
Mol File:
136194-77-9.mol
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GO 6976 Chemical Properties

Boiling point:
652.3±55.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
Off-white solid
pka
14.39±0.20(Predicted)
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Safety Information

Safety Statements 
22-24/25
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GO 6976 Usage And Synthesis

Biological Activity

Potent protein kinase C (PKC) inhibitor (IC 50 = 7.9 nM). In vitro, discriminates between Ca 2+ -dependent and -independent isoforms of PKC; selectively inhibits PKC α and PKC β 1 (IC 50 values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKC δ , - ε , or - ζ (IC 50 > 3 μ M). Also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC 50 values are 5, 30, 130 and 370 nM respectively).

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GO 6976SupplierMore

Shanghai Boyle Chemical Co., Ltd.
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sales@boylechem.com
J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
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jkinfo@jkchemical.com;market6@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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86-21-50328103 * 801、802、803、804 Mobile:18930552037
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3bsc@sina.com
Chemsky (shanghai) International Co.,Ltd
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021-50135380
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shchemsky@sina.com
BOC Sciences
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Email:
info@bocsci.com
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