Basic information Antipyretic analgesic Chemical property Pharmacological Actions Pharmacokinetics Preparation method Usage and Dosage Application in Particular Diseases Adverse reaction Taboo Notes Drug interactions Usage Administration nursing care point Production Safety Related Supplier
Acetaminophen Structure

Acetaminophen

Chemical Properties

Melting point 168-172 °C(lit.)
Boiling point 273.17°C (rough estimate)
Density  1,293 g/cm3
vapor pressure  0.008Pa at 25℃
refractive index  1.5810 (rough estimate)
Flash point 11 °C
storage temp.  Inert atmosphere,Room Temperature
solubility  ethanol: soluble0.5M, clear, colorless
pka 9.86±0.13(Predicted)
form  Crystals or Crystalline Powder
color  White
PH 5.5-6.5 (H2O, 20℃)(saturated solution)
PH Range 5.5 - 6.5 (H?O, 20 °C) (saturated solution)
Odor odorless
explosive limit 15%(V)
Water Solubility  14 g/L (20 ºC)
Merck  14,47
BRN  2208089
BCS Class 3,4
InChIKey RZVAJINKPMORJF-UHFFFAOYSA-N
LogP 1.098 at 25℃
CAS DataBase Reference 103-90-2(CAS DataBase Reference)
IARC 3 (Vol. 50, 73) 1999
NIST Chemistry Reference Acetaminophen(103-90-2)
EPA Substance Registry System Acetaminophen (103-90-2)

Safety Information

Hazard Codes  Xn,T,F
Risk Statements  22-36/37/38-52/53-36/38-40-39/23/24/25-23/24/25-11
Safety Statements  26-36-61-37/39-22-45-36/37-16-7
RIDADR  UN 3077 9/PG III
WGK Germany  1
RTECS  AE4200000
Autoignition Temperature 540 °C
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29242930
Hazardous Substances Data 103-90-2(Hazardous Substances Data)
Toxicity LD50 in mice (mg/kg): 338 orally (Starmer), 500 i.p. (Dahlin, Nelson)

MSDS

Usage And Synthesis

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Question and answer