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Sulfanilic acid

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Sulfanilic acid Basic information

Product Name:
Sulfanilic acid
CAS:
121-57-3
MF:
C6H7NO3S
MW:
173.19
EINECS:
204-482-5
Mol File:
121-57-3.mol
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Sulfanilic acid Chemical Properties

Melting point:
>300 °C(lit.)
Density 
1.485
refractive index 
1.5500 (estimate)
storage temp. 
Store in dark!
solubility 
10g/l
pka
3.24(at 25℃)
form 
solid
PH
2.5 (10g/l, H2O, 20℃)
Water Solubility 
0.1 g/100 mL (20 ºC)
Merck 
14,8926
BRN 
908765
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
HVBSAKJJOYLTQU-UHFFFAOYSA-N
CAS DataBase Reference
121-57-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzenesulfonic acid, 4-amino-(121-57-3)
EPA Substance Registry System
Sulfanilic acid (121-57-3)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
36/38-43-34
Safety Statements 
26-36/37/39-45-37-24-36/37
RIDADR 
UN 2790 8/PG 3
WGK Germany 
1
RTECS 
WP3895500
Autoignition Temperature
>400 °C
TSCA 
Yes
HS Code 
29214210
Hazardous Substances Data
121-57-3(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 12300 mg/kg

MSDS

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Sulfanilic acid Usage And Synthesis

Description

Sulfanilic acid (4-amino benzene sulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions. The solid acid exists as a zwitterion, and has an unusually high melting point.

Chemical Properties

greyish-white crystals or powder

Uses

A toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.

Definition

ChEBI: An aminobenzenesulfonic acid that is aniline sulfonated at the para-position.

Application

As the compound readily form diazo compounds, it is used to make dyes and sulpha drugs . This property is also used for the quantitative analysis of nitrate and nitrite ions by diazonium coupling reaction with N-(1-Naphthyl) ethylene diamine , resulting in an azo dye, and the concentration of nitrate or nitrite ions were deduced from the color intensity of the resulting red solution by colorimetry.
It is also used as a standard in combustion analysis.

General Description

White powder with faint purple tinge. Grayish-white flat crystals. Becomes anhydrous at around 212°F. Low toxicity (used medicinally).

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Sulfanilic acid is an amino acid. Reacts weakly with both acids and bases.

Fire Hazard

Flash point data for Sulfanilic acid are not available, however Sulfanilic acid is probably combustible.

Chemical Synthesis

Sulfanilic acid can be produced by sulfonation of aniline.

Purification Methods

Crystallise the acid (as dihydrate) from boiling water. Dry it at 105o for 2-3hours, then over 90% H2SO4 in a vacuum desiccator. The S-benzylisothiuronium salt has m 187o (from aqueous EtOH). [Beilstein 14 IV 2655.]

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Sulfanilic acidSupplierMore

Shanghai Yolne Chemical Co., Ltd. Gold
Tel:
021-61525205;021-62960152
Email:
sales@yolne.com;sales@yolne.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD Gold
Tel:
021-20337333-801
Email:
market@aladdin-e.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
821-50328103-801
Email:
3bsc@sina.com
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