Sulfanilic acid Chemical Properties
- Melting point:
- >300 °C(lit.)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Store in dark!
- 3.24(at 25℃)
- 2.5 (10g/l, H2O, 20℃)
- Water Solubility
- 0.1 g/100 mL (20 ºC)
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 121-57-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenesulfonic acid, 4-amino-(121-57-3)
- EPA Substance Registry System
- Sulfanilic acid (121-57-3)
- Hazard Codes
- Risk Statements
- Safety Statements
- UN 2790 8/PG 3
- WGK Germany
- Autoignition Temperature
- >400 °C
- HS Code
- Hazardous Substances Data
- 121-57-3(Hazardous Substances Data)
- LD50 orally in Rabbit: 12300 mg/kg
Sulfanilic acid Usage And Synthesis
Sulfanilic acid (4-amino benzene sulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions. The solid acid exists as a zwitterion, and has an unusually high melting point.
greyish-white crystals or powder
A toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.
ChEBI: An aminobenzenesulfonic acid that is aniline sulfonated at the para-position.
As the compound readily form diazo compounds, it is used to make dyes and sulpha drugs . This property is also used for the quantitative analysis of nitrate and nitrite ions by diazonium coupling reaction with N-(1-Naphthyl) ethylene diamine , resulting in an azo dye, and the concentration of nitrate or nitrite ions were deduced from the color intensity of the resulting red solution by colorimetry.
It is also used as a standard in combustion analysis.
White powder with faint purple tinge. Grayish-white flat crystals. Becomes anhydrous at around 212°F. Low toxicity (used medicinally).
Air & Water Reactions
Insoluble in water.
Sulfanilic acid is an amino acid. Reacts weakly with both acids and bases.
Flash point data for Sulfanilic acid are not available, however Sulfanilic acid is probably combustible.
Sulfanilic acid can be produced by sulfonation of aniline.
Crystallise the acid (as dihydrate) from boiling water. Dry it at 105o for 2-3hours, then over 90% H2SO4 in a vacuum desiccator. The S-benzylisothiuronium salt has m 187o (from aqueous EtOH). [Beilstein 14 IV 2655.]
Sulfanilic acid Preparation Products And Raw materials
- CHLORANTINE FAST RED 5B
- Eriochrome Black T
- ACID ORANGE 63
- ACID YELLOW 25
- REACTIVE BLUE 4
- Folic acid
- O-SULFANILIC ACID,2-Aminobenzenesulfonic acid, o-Sulfanilic acid, Orthanilic acid,2-Aminobenzenesulfonic acid, o-Sulfanilic acid
- Ascoric Acid
- Stearic acid
- Citric acid
- SULFANILIC ACID SODIUM SALT
- 4-Aminobenzoic acid
- M-SULFANILIC ACID
- Sulfanilic acid
- Ethyl 2-(Chlorosulfonyl)acetate
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