Trimethylsilyl cyanide
Trimethylsilyl cyanide Basic information
- Product Name:
- Trimethylsilyl cyanide
- CAS:
- 7677-24-9
- MF:
- C4H9NSi
- MW:
- 99.21
- EINECS:
- 231-657-3
- Mol File:
- 7677-24-9.mol
Trimethylsilyl cyanide Chemical Properties
- Melting point:
- 8-11 °C(lit.)
- Boiling point:
- 114-117 °C(lit.)
- Density
- 0.793 g/mL at 20 °C(lit.)
- refractive index
- n
20/D 1.392(lit.)
- Flash point:
- 34 °F
- storage temp.
- 0-6°C
- solubility
- Miscible with organic solvents.
- form
- liquid
- Water Solubility
- reacts
- Sensitive
- Moisture Sensitive
- BRN
- 1737612
- InChIKey
- LEIMLDGFXIOXMT-UHFFFAOYSA-N
- CAS DataBase Reference
- 7677-24-9(CAS DataBase Reference)
- EPA Substance Registry System
- Silanecarbonitrile, trimethyl- (7677-24-9)
Safety Information
- Hazard Codes
- F,T+,T,N
- Risk Statements
- 11-26/27/28-29-50/53
- Safety Statements
- 16-36/37/39-45-61-28A-26
- RIDADR
- UN 3384 6.1/PG 1
- WGK Germany
- 3
- F
- 10-21
- Hazard Note
- Highly Flammable/Toxic
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29310095
MSDS
- Language:EnglishProvider:Cyanotrimethylsilane
- Language:EnglishProvider:SigmaAldrich
- Language:EnglishProvider:ACROS
- Language:EnglishProvider:ALFA
Trimethylsilyl cyanide Usage And Synthesis
Chemical Properties
clear colorless to yellow liquid
Uses
Reacts with aldehydes and ketones to give cyanohydrin-TMS ethers which can be reduced to β-aminoethyl alcohols.
Uses
Trimethylsilyl Cyanide is used as a reagent in the synthesis of optically active cyanohydrins. Used in the preparation of Reissert compounds, which represent reactive polyamides. Toxic to humans.
Purification Methods
The material should have only one sharp signal in the 1H NMR (in CCl4 with CHCl3 as internal standard) : 0.4ppm and IR with max at 2210cm1 [McBride & Beachall J Am Chem Soc 74 5247 1952, Prober J Am Chem Soc 77 3224 1955]; otherwise purify it by fractionating through an 18 x 1/4inch column. [Evers et al. J Am Chem Soc 81 4493 1959.] It has also been carefully distilled using a 60cm vacuum jacketed column. If the volume of sample is small, the cyanide can be chased (in the distillation) with xylene that had been previously distilled over P2O5. It is HIGHLY TOXIC and FLAMMABLE. [Evans et al. J Org Chem 39 914 1974, Beilstein 4 IV 3893.]
Trimethylsilyl cyanide Preparation Products And Raw materials
Preparation Products
Raw materials
Trimethylsilyl cyanide(7677-24-9)Related Product Information
- METHYLSILANE
- Tosylmethyl isocyanide
- Dichloromethylvinylsilane
- POTASSIUM CYANIDE
- HYDROGEN CYANIDE
- Iodotrimethylsilane
- Cyanide
- IRON SILICIDE
- Dichlorodimethylsilane
- TRIMETHYLSILANE
- Trimethylsilyl cyanide
- Bromotrimethylsilane
- MAGNESIUM SILICIDE
- tert-Butyldimethylsilyl chloride
- Chloromethyltrimethylsilane
- N-(Trimethylsilyl)acetamide
- (Trifluoromethyl)trimethylsilane
- sodium cyanide
Trimethylsilyl cyanideSupplierMore
- Tel:
- Please Send Email QQ:18652950785
- Email:
- chemweiao@163.com
- Tel:
- 010-82848833- ;010-82848833-
- Email:
- jkinfo@jkchemical.com;market6@jkchemical.com
- Tel:
- 400 025 5188
- Email:
- sales_china@pharmablock.com
- Tel:
- +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
- Email:
- sh@meryer.com
- Tel:
- 010-88425576
- Email:
- sales@dhltchem.com