ChemicalBook >  Product Catalog >  Organic Chemistry >  Inorganic acid Esters >  Triethyl phosphate

Triethyl phosphate

Basic information Safety Related Supplier

Triethyl phosphate Basic information

Product Name:
Triethyl phosphate
CAS:
78-40-0
MF:
C6H15O4P
MW:
182.15
EINECS:
201-114-5
Mol File:
78-40-0.mol
More
Less

Triethyl phosphate Chemical Properties

Melting point:
-56 °C
Boiling point:
215 °C(lit.)
Density 
1.072 g/mL at 25 °C(lit.)
vapor density 
6.28 (vs air)
vapor pressure 
1 mm Hg ( 40 °C)
refractive index 
n20/D 1.403(lit.)
Flash point:
240 °F
storage temp. 
Store below +30°C.
solubility 
500g/l (slow decomposition)
form 
Liquid
Specific Gravity
1.072
color 
Clear
PH
7 (H2O, 20℃)
explosive limit
1.2-10%(V)
Water Solubility 
SOLUBLE
Hydrolytic Sensitivity
7: reacts slowly with moisture/water
Merck 
14,9674
BRN 
1705772
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, water.
InChIKey
DQWPFSLDHJDLRL-UHFFFAOYSA-N
CAS DataBase Reference
78-40-0(CAS DataBase Reference)
NIST Chemistry Reference
Triethyl phosphate(78-40-0)
EPA Substance Registry System
Triethyl phosphate (78-40-0)
More
Less

Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
25-26
RIDADR 
3278
WGK Germany 
1
RTECS 
TC7900000
Autoignition Temperature
845 °F
TSCA 
Yes
HS Code 
29190090
Hazardous Substances Data
78-40-0(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1165 mg/kg

MSDS

More
Less

Triethyl phosphate Usage And Synthesis

Chemical Properties

Triethyl phosphate is a colorless, high-boiling liquid and containing 17 wt % phosphorus; mild odor. Very stable at ordinary temperatures, compatible with many gums and resins, soluble in most organic solvents, miscible with water. When mixed with water is quite stable at room temperature, but at elevated temperatures it hydrolyzes slowly. Combustible.It is manufactured from diethyl ether and phosphorus pentoxide via a metaphosphate intermediate.
Triethyl phosphate
Triethyl phosphate has been used commercially as an additive for polyester laminates and in cellulosics. In polyester resins it functions as a viscosity depressant and as a flame retardant. The viscosity-depressant effect of triethyl phosphate in polyester resin permits high loadings of alumina trihydrate, a fire- retardant smoke-suppressant filler. Triethyl phosphate has also been employed as a flame-resistant plasticizer in cellulose acetate. Because of its water solubility, the use of triethyl phosphate is limited to situations where weathering resistance is unimportant. The halogenated alkyl phosphates are generally used for applications where lower volatility and greater resistance to leaching are required.

Uses

Triethyl phosphate is use as a flame retardant in the manufacture of polyisocyanurate (PIR) and polyurethane (PUR) foam insulation and thermoset plastic products. The chemical compound is also used as a viscosity reducer in plastic resins, and as a catalyst, solvent or intermediate in the production of pesticides, pharmaceuticals, lacquers and other products.As ethylating agent; formation of polyesters which are used as insecticides.

Definition

ChEBI: A trialkyl phosphate that is the triethy ester derivative of phosphoric acid.

Production Methods

Prepared by the reaction of tetraethyl hypophosphate with ethanol in the presence of aluminum ethoxide or by treating triethyl phosphate with diethyl hydrogen phosphate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 25, p. 1000, 1960 DOI: 10.1021/jo01076a035

General Description

A colorless, corrosive liquid. Combustible. Slowly dissolves in water and sinks in water. Severely irritates skin, eyes and mucous membranes.

Air & Water Reactions

Slowly dissolves in water with slight decomposition .

Reactivity Profile

Organophosphates, such as Triethyl phosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Health Hazard

May be harmful by inhalation, ingestion or absorption. May cause irritation.

Fire Hazard

Special Hazards of Combustion Products: May produce hazardous decomposition products such as carbon dioxide, carbon monoxide and oxides of phosphorus.

Industrial uses

1 Plasticizer for cellulose acetate, resins, plastics, gums.
2 Flame retardant additive in unsaturated polyester resins.
3 Solvent; lacquer remover.
4 Catalyst.
5 Chemical intermediate; ethylating agent.

Safety Profile

Moderately toxic by ingestion, intraperitoneal, and intravenous routes. Experimental reproductive effects. Mutation data reported. Causes cholinesterase inhibition, but to a lesser extent than parathion. May be expected to cause nerve injury similar to that of other phosphate esters. Triethyl phosphate is stable under normal conditions of use. Avoid contact with strong bases and oxidizing agents. Triethyl phosphate is combustible at high temperatures. Heating to decomposition may release carbon dioxide, carbon monoxide, phosphorus oxides and other potentially toxic fumes or gases. Avoid heat, open flames and other potential sources of ignition.

Environmental Fate

Triethyl phosphate is not readily biodegradable. An accidental release of vapors to air, or liquid to soils or water, will degrade slowly in the environment. Releases to water may pose a danger to fish (low toxicity), invertebrates (low toxicity) and aquatic plants (low toxicity) prior to degradation. The chemical is not expected to adsorb to suspended soils and sediments.

Metabolism

A system utilizing isolated anterior forearm stratum corneum conjunctum of man to study skin penetrating capacity of a series of organic phosphates was developed. Trimethyl phosphate was the most penetrating, followed by triethyl phosphate, in a series of 8 trialkyl esters (Marzulli et al 1965).
Rats treated orally at 100 mg/kg and mice treated i.p. at 1000 mg/kg with [32P]-labeled triethyl phosphate excreted diethyl phosphate in the urine. No parent compound was detected in the urine of either species. S-Ethyl cysteine and S-ethyl cysteine N-acetate were also isolated. The compound was excreted very rapidly, with 90% of the administered dose in the urine in 16 h and nearly 100% within 96 h (Jones 1970).

Purification Methods

Dry the ester by refluxing it with solid BaO and then fractionally distil it under reduced pressure. It is kept over Na and distilled. Store it in the receiver protected from light and moisture. Alternatively it is dried over Na2SO4 and distilled under reduced pressure. The middle fraction is stirred for several weeks over anhydrous Na2SO4 and again fractionated under reduced pressure until the specific conductance reaches a constant low value of 25 1.19 x 108, 40 1.68 x 108, and 55 2.89 x 108 ohm-1 cm. It has also been fractionated carefully under reduced pressure through a glass helices-packed column. It is soluble in EtOH, Et2O and H2O (dec). [Estok & Wendlandt J Am Chem Soc 77 4767 1955, Hoffmann et al. J Am Chem Soc 78 6413 1956, (P NMR) Muller et al. J Am Chem Soc 78 3557 1956, French et al. J Chem Soc 3582 1959, IR: Bellamy & Beecher J Chem Soc 475 1952 and McIvor Can J Chem 36 820 1958, Kosolapoff Organophosphorus Compounds, Wiley p 258 1950, Beilstein 1 IV 1339.]

More
Less

Triethyl phosphateSupplierMore

Qingdao Changrong Chemical Science &u Technology Co,Ltd Gold
Tel:
13969711385 0532-58975871-
Email:
3001133099@qq.com
Zhangjiagang create Material Co., Ltd. Gold
Tel:
0512-58361933
Email:
2624018324@qq.com
ZhangJiaGang YaRui Chemical Co.,Ltd. Gold
Tel:
18921980669 0512-58961066-
Email:
sales@yaruichem.com
Hangzhou Xingui Industrial Co., Ltd. Gold
Tel:
15306520585
Email:
1842956942@qq.com
Tianjin Zhongxin Chemtech Co., Ltd.
Tel:
022-66880623
Email:
sales@tjzxchem.com;sales@tjzxchem.com
Basic information Safety Related Supplier