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3-Methyl-2-butanone

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3-Methyl-2-butanone Basic information

Product Name:
3-Methyl-2-butanone
CAS:
563-80-4
MF:
C5H10O
MW:
86.13
EINECS:
209-264-3
Mol File:
563-80-4.mol
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3-Methyl-2-butanone Chemical Properties

Melting point:
−92 °C(lit.)
Boiling point:
94-95 °C(lit.)
Density 
0.805 g/mL at 25 °C(lit.)
vapor pressure 
53.33 hPa (19.9 °C)
refractive index 
n20/D 1.388(lit.)
Flash point:
6 °C
storage temp. 
Flammables area
solubility 
water: soluble8.21g/L at 20°C
form 
Liquid
color 
Clear colorless
explosive limit
1.5-9%(V)
Odor Threshold
0.5ppm
Water Solubility 
6 g/L (20 ºC)
Merck 
14,6090
BRN 
1071238
Exposure limits
TLV-TWA 700 mg/m3 (200 ppm); STEL 875 mg/m3 (250 ppm) (ACGIH).
InChIKey
SYBYTAAJFKOIEJ-UHFFFAOYSA-N
CAS DataBase Reference
563-80-4(CAS DataBase Reference)
NIST Chemistry Reference
2-Butanone, 3-methyl-(563-80-4)
EPA Substance Registry System
Methyl isopropyl ketone (563-80-4)
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Safety Information

Hazard Codes 
F
Risk Statements 
11-67
Safety Statements 
9-16-33
RIDADR 
UN 2397 3/PG 2
WGK Germany 
1
RTECS 
EL9100000
Autoignition Temperature
475 °C
Hazard Note 
Highly Flammable
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29141990
Toxicity
LD50 orally in male mice: 29.86 mmol/kg (Tanii)

MSDS

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3-Methyl-2-butanone Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS LIQUID

Chemical Properties

MIPK is a colorless liquid with an acetonelike odor.

Uses

Methyl isopropyl ketone (MIPK) is used asa solvent for lacquers.

Uses

Solvent for nitrocellulose lacquers.

General Description

A colorless liquid with a pleasant odor. Flash point below 70°F. Less dense than water. May be toxic by inhalation and skin absorption. Used as a solvent.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Ketones, such as 3-Methyl-2-butanone, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Hazard

Toxic material. Embryo/fetal damage andneonatal toxicity.

Health Hazard

Irritating to the eyes, nose, throat, upper respiratory tract, and skin.

Health Hazard

The acute toxic effects from exposure to thevapors of MIPK are narcosis and irritationof the eyes, skin, and respiratory passages.In rabbits the irritation effect of 100 mg fora 24-hour exposure was mild in the eyes,while 500 mg was moderate on the skin. Thetoxicity data on this compound are too scant.In general, its toxicity is low and narcosissymptoms in humans may be felt only at veryhigh concentrations. In guinea pigs exposureto 5000 ppm caused coma.

Fire Hazard

Special Hazards of Combustion Products: Acrid smoke and fumes

Safety Profile

Poison by ingestion. Mildly toxic by inhalation and skin contact. Mutation data reported. A skin and eye irritant. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes.

Potential Exposure

This ketone is used as a solvent for nitrocellulose lacquers.

Shipping

UN23973-Methylbutan-2-one, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Reflux the ketone with a little KMnO4. Fractionate it through a spinning-band column, dry with CaSO4 and distil it. [Beilstein 1 IV 3287.]

Incompatibilities

Vapors may form explosive mixture with air. Ketones are incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, nitrated amines, azo, diazo, azido compounds, carbamates, organic cyanates

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

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3-Methyl-2-butanoneSupplierMore

Jinan Jason Pharmaceutical Co., Ltd. Gold
Tel:
0531-82956131 15069164249
Email:
jnjspharm@126.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
INTATRADE GmbH
Tel:
+49 3493/605464
Email:
sales@intatrade.de
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
821-50328103-801
Email:
3bsc@sina.com
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