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6-Bromoquinoline

Basic information Bromoquinoline Application and synthetic method Safety Related Supplier

6-Bromoquinoline Basic information

Product Name:
6-Bromoquinoline
CAS:
5332-25-2
MF:
C9H6BrN
MW:
208.05
EINECS:
226-238-7
Mol File:
5332-25-2.mol
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6-Bromoquinoline Chemical Properties

Melting point:
19°C
Boiling point:
116 °C / 6mmHg
Density 
1.55
refractive index 
n20/D 1.663
Flash point:
19 °C
storage temp. 
Refrigerator
solubility 
Soluble in acetone, acetonitrile, dichloromethane, ethyl acetate and THF.
pka
4.18±0.10(Predicted)
InChIKey
IFIHYLCUKYCKRH-UHFFFAOYSA-N
CAS DataBase Reference
5332-25-2(CAS DataBase Reference)
NIST Chemistry Reference
6-Bromo quinoline(5332-25-2)
EPA Substance Registry System
Quinoline, 6-bromo- (5332-25-2)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22-20/21/22
Safety Statements 
26-37/39-39-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29334900
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6-Bromoquinoline Usage And Synthesis

Bromoquinoline

There are seven positional isomers of bromoquinoline and their main properties are listed below: There are seven positional isomers of bromoquinoline and their main properties are listed

Application and synthetic method

3-bromo-quinoline is reacted with mixed acid for generating 3-bromo-5-nitro-quinoline, which heats together with potassium permanganate for being oxidation into 5-bromo-2, 3-pyridine dicarboxylic acid.
6-bromo-quinoline is heated together with nitric acid to generate 6-bromo-8-nitro quinolone with further reaction with potassium permanganate for being oxidized to 2, 3-pyridinedicarboxylic acid.
2-bromo-quinolien can be synthesized through the reaction between 2-hydroxy quinoline and phosphorus pentabromide.
Quinoline perbromide is heated at 180 °C for generating 3-bromo-quinoline.
From the heating between 4-hydroxy quinoline and phosphorus pentabromide, or from the diazotization reaction via 4-aminoquinoline to generate 4-bromo-quinoline;
5-bromo-quinoline is synthesize by the heating reaction between m-bromo-aniline, glycerol, m-bromo nitrobenzene and concentrated sulfuric acid, or from the diazotization reaction of 5-aminoquinoline.
6-bromo-quinoline can be synthesized from the heating of bromoaniline, glycerol, concentrated sulfuric acid, and p-bromo-nitrobenzene. 7-bromo-quinoline can be synthesized from the diazotization reaction of 7-aminoquinoline.
8-bromo-quinoline can be synthesized from the heating reaction of o-bromo-aniline, glycerol, concentrated sulfuric acid and o-bromo nitrobenzene.
application: as organic synthesis reagents.
The above information is edited by the Chemicalbook of Dai Xiongfeng.

Chemical Properties

Thick Oil

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6-BromoquinolineSupplierMore

Shanghai Harvest Chemical Industrial Co., Ltd. Gold
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21-31038972-
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ammyzuo@harvest-chem.com;
Chengdu Forest Science and Technology Development Co., Ltd. Gold
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028-87925786-
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China Synchem Technology Co.,Ltd. Gold
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552-4929304- ;0552-4929304- ;0552-4929304-
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wxh@cnsynchem.com;sales@cnsynchem.com;wxh@cnsychem.com
Nanjing Habo Medical Technology Co., Ltd. Gold
Tel:
025-85760892-
Email:
sales@habotech.com;
Yichang Zhongyitai Trading Co., Ltd. Gold
Tel:
0717-6449896
Email:
root@zhongyitai.com
Basic information Bromoquinoline Application and synthetic method Safety Related Supplier