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RESCINNAMINE

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RESCINNAMINE Basic information

Product Name:
RESCINNAMINE
CAS:
24815-24-5
MF:
C35H42N2O9
MW:
634.72
EINECS:
246-471-8
Mol File:
24815-24-5.mol
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RESCINNAMINE Chemical Properties

Melting point:
238-239°C
alpha 
D24 -97° (c = 1 in chloroform)
Boiling point:
669.26°C (rough estimate)
Density 
1.2161 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
2-8°C
pka
pKa 6.4 (Uncertain)
Stability:
Stable, but darkens slowly in light. Incompatible with strong oxidizing agents.
EPA Substance Registry System
Rescinnamine (24815-24-5)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
25-20/21/22
Safety Statements 
22-45-36
RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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RESCINNAMINE Usage And Synthesis

Chemical Properties

white to cream powder

Uses

Rescinnamine occurs in the roots of a num ber of Rauwolfia species. Therapeutically, itis used as an antihypertensive agent.

brand name

Moderil (Pfizer).

General Description

Odorless white to cream colored crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

The neat material darkens slowly on exposure to light. In solution this occurs more rapidly. .

Health Hazard

The pharmacological properties of rescinnamine are similar to those of reserpine, butthe side effects are low. It acts as a sedativeand hypotensive. A dose of 0.25 mg/day mayproduce the effect of sleepiness in humans.Excessive doses may produce depression,nightmare, nausea, diarrhea, and hypotension.
LD50 value, oral (rats): 1000 mg/kg
The carcinogenicity of rescinnamine inanimals or humans is unknown.

Fire Hazard

Flash point data for RESCINNAMINE are not available. RESCINNAMINE is probably combustible.

Purification Methods

Crystallise it from *benzene, MeOH or aqueous Me2CO. The hydrochloride has m 232o(dec) (from MeOH) and [] D -74o (MeOH). It is an antihypertensive. [Klohs et al. J Am Chem Soc 77 2241 1955, Beilstein 25 III/IV 1323.]

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RESCINNAMINESupplierMore

Beijing HuaMeiHuLiBiological Chemical
Tel:
010-56205725;010-86181995
Email:
waley188@sohu.com
Nanjing Sunlida Biological Technology Co., Ltd.
Tel:
025-58378339;025-57798810
Email:
sales@sunlidabio.com;sales@sunlidabio.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel:
0510-85629785-
Email:
sales@reading-chemicals.com;
Wuhan ChemFaces Biochemical Co., Ltd.
Tel:
Email:
aileen@chemfaces.com
EMMX Biotechnology LLC
Tel:
888-539-0666
Email:
info@emmx.com
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