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PHORBOL 12-MYRISTATE 13-ACETATE

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PHORBOL 12-MYRISTATE 13-ACETATE Basic information

Product Name:
PHORBOL 12-MYRISTATE 13-ACETATE
CAS:
16561-29-8
MF:
C36H56O8
MW:
616.83
EINECS:
605-413-5
Mol File:
16561-29-8.mol
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PHORBOL 12-MYRISTATE 13-ACETATE Chemical Properties

Boiling point:
571.87°C (rough estimate)
Density 
1.17±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.4900 (estimate)
storage temp. 
−20°C
solubility 
DMSO: DMSO solutions can be stored dark at −20?#x00b0;C for at least six months.soluble
form 
Fine Crystalline Powder
pka
11.19±0.70(Predicted)
color 
Off-white to light yellow
Water Solubility 
Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.
Sensitive 
Light Sensitive
BRN 
2407201
InChIKey
PHEDXBVPIONUQT-RGYGYFBISA-N
CAS DataBase Reference
16561-29-8(CAS DataBase Reference)
EPA Substance Registry System
12-O-Tetradecanoylphorbol 13-acetate (16561-29-8)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
38-36/37/38
Safety Statements 
36/37-26
RIDADR 
2928
WGK Germany 
3
RTECS 
QH4377000
8-10
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29153900

MSDS

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PHORBOL 12-MYRISTATE 13-ACETATE Usage And Synthesis

Chemical Properties

white to off-white solid

General Description

White crystals.

Air & Water Reactions

Practically water insoluble.

Reactivity Profile

PHORBOL 12-MYRISTATE 13-ACETATE is sensitive to acids and alkalis. .

Fire Hazard

Flash point data for PHORBOL 12-MYRISTATE 13-ACETATE are not available; however, PHORBOL 12-MYRISTATE 13-ACETATE is probably combustible.

Biological Activity

Extensively used phorbol ester activator of protein kinase C; tumor promoter. Binds to PKC with a K i value of 2.6 nM as measured by displacement of [ 3 H]phorbol 12,13-dibutyrate binding in rat cortex synaptosomal membranes.

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PHORBOL 12-MYRISTATE 13-ACETATESupplierMore

Nanjing Spring & Autumn Biological Engineering Co., Ltd. Gold
Tel:
13815430202 025-84430028-
Email:
sale02@cqherb.com
Chengdu Push Bio-Technology Co., Ltd. Gold
Tel:
18080489829
Email:
3004654993@qq.com
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
400-660-8290 21-61259100-
Email:
sh@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
18930552037 821-50328103-801
Email:
3bsc@sina.com
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