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Propacetamol

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Propacetamol Basic information

Product Name:
Propacetamol
CAS:
66532-85-2
MF:
C14H20N2O3
MW:
264.32
EINECS:
266-390-1
Mol File:
66532-85-2.mol
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Propacetamol Chemical Properties

Melting point:
55-57 °C
Boiling point:
434.5±30.0 °C(Predicted)
Density 
1.132±0.06 g/cm3(Predicted)
pka
14.20±0.70(Predicted)
CAS DataBase Reference
66532-85-2(CAS DataBase Reference)
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Propacetamol Usage And Synthesis

Description

Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.

Uses

Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.

Contact allergens

Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).

Propacetamol Preparation Products And Raw materials

Raw materials

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PropacetamolSupplierMore

TAIYUAN RHF CO.,LTD.
Tel:
+86 351 7031519
Email:
sales@RHFChem.com
LGM Pharma
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1-(800)-881-8210
Email:
inquiries@lgmpharma.com
Shanghai Longsheng chemical Co.,Ltd.
Tel:
021-58099637-8009;021-58099652-8005
Email:
sales@shlschem.com;bin.wu@shlschem.com
Nanjing Chemlin Chemical Co., Ltd
Tel:
025-83697070
Email:
info@chemlin.com.cn
XiaoGan ShenYuan ChemPharm co,ltd
Tel:
0712-2580635- ;0712-2580635
Email:
1791901229@qq.com;1791901229@qq.com;
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