N-Methylpiperidine Chemical Properties
- Melting point:
- -50 °C
- Boiling point:
- 106-107 °C(lit.)
- 0.817 g/mL at 20 °C(lit.)
- refractive index
- Flash point:
- 38 °F
- storage temp.
- 10.08(at 25℃)
- Clear colorless
- 12 (100g/l, H2O, 20℃)
- explosive limit
- Water Solubility
- CAS DataBase Reference
- 626-67-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Piperidine, 1-methyl-(626-67-5)
- EPA Substance Registry System
- Piperidine, 1-methyl- (626-67-5)
N-Methylpiperidine Usage And Synthesis
CLEAR COLOURLESS LIQUID
Reactant for: ·sp3 C-H Bond activation with ruthenium(II) catalysts and C(3)-alkylation of cyclic amines ·One-pot synthesis of Z-cinnamic acids Reactant for synthesis of: ·Unsymmetrical ureas ·Antibacterial imidazolium, pyrrolidinium, and piperidinium salts ·C1-C16 segment of goniodomin A via palladium-catalyzed organostannane thioester coupling ·Multi-targeted inhibitors of insulin-like growth factor-1 receptor and members of ErbB-family receptor kinases
A colorless liquid with the odor of pepper. Density 0.816 g / cm3 and flash point 38°F. May irritate skin and eyes. Vapors heavier than air. Used as a solvent and to make other chemicals.
Air & Water Reactions
Highly flammable. Soluble in water.
N-Methylpiperidine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Poison by intraperitoneal and subcutaneous routes. A very dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NOx.
N-Methylpiperidine Preparation Products And Raw materials
- TROPINE-N-OXIDE DIHYDRATE, 99
- 010-82848833- ;010-82848833-
- 400-610-6006; 021-67582000
- 021-67121386 / 800-988-0390
- 13651141086; 86(10)60275028、60275820