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D-(-)-PANTOLACTONE

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D-(-)-PANTOLACTONE Basic information

Product Name:
D-(-)-PANTOLACTONE
CAS:
599-04-2
MF:
C6H10O3
MW:
130.14
EINECS:
209-963-3
Mol File:
599-04-2.mol
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D-(-)-PANTOLACTONE Chemical Properties

Melting point:
91 °C(lit.)
Boiling point:
120-122 °C15 mm Hg(lit.)
Density 
1.1066 (rough estimate)
refractive index 
-50.8 ° (C=2, H2O)
Flash point:
120-122°C/15mm
storage temp. 
2-8°C
pka
13.12±0.40(Predicted)
form 
Crystals or Crystalline Powder
color 
White
optical activity
[α]25/D 49.8°, c = 2 in H2O
Water Solubility 
almost transparency
Sensitive 
Hygroscopic
Merck 
14,7013
BRN 
80957
InChIKey
SERHXTVXHNVDKA-BYPYZUCNSA-N
CAS DataBase Reference
599-04-2(CAS DataBase Reference)
EPA Substance Registry System
Pantolactone (599-04-2)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
1
3-10
TSCA 
Yes
HS Code 
29322090

MSDS

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D-(-)-PANTOLACTONE Usage And Synthesis

Chemical Properties

WHITE CRYSTALLINE POWDER OR CRYSTALS

Uses

D-(-)-PANTOLACTONE is an important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.

Purification Methods

Recrystallise the lactone from Et2O/pet ether, diisopropyl ether or *C6H6/pet ether and sublime it at 25o/0.0001mm. It hydrolyses readily to the hydroxy-acid and racemises when heated above 145o. The Brucine salt has m 211-212o (from EtOH). [Kuhn & Wieland Chem Ber 73 1134 1940, and Stiller et al. J Am Chem Soc 62 1779 1940, Bental & Tishler J Am Chem Soc 68 1463 1946, Beilstein 18/1 V 22.]

D-(-)-PANTOLACTONE Preparation Products And Raw materials

Raw materials

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D-(-)-PANTOLACTONESupplierMore

HuBei ShengBaoLai Biological Technology Co., Ltd Gold
Tel:
13007105135
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sbl1120@163.com;2547724091@qq.com;
Nanjing Jinhao Pharmaceutical Co., Ltd. Gold
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13382796873
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hjz8008@163.com
Jiangyin Ligang 2nd Chemical Co., Ltd. Gold
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15961517070 0510-86631396
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82871124@qq.com
Shanghai Boyle Chemical Co., Ltd.
Tel:
Mr Qiu:021-50182298(Demestic market) Miss Xu:021-50180596(Abroad market)
Email:
sales@boylechem.com
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
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