NOGALAMYCIN

Basic information Safety Related Supplier

NOGALAMYCIN Basic information

Product Name:
NOGALAMYCIN
CAS:
1404-15-5
MF:
C39H49NO16
MW:
787.8
Mol File:
1404-15-5.mol
More
Less

NOGALAMYCIN Chemical Properties

Melting point:
195-196° (dec)
alpha 
D25 +425° (c = 0.11 in CHCl3)
Boiling point:
658.61°C (rough estimate)
Density 
1.2095 (rough estimate)
refractive index 
1.7650 (estimate)
storage temp. 
2-8°C
pka
7.45 (60% ethanol)
color 
Orange-red solid from MeOH
More
Less

Safety Information

Hazard Codes 
T
Risk Statements 
45-46-61-20/21/22
Safety Statements 
53-22-36/37/39-45
WGK Germany 
3
RTECS 
RA4550000
Toxicity
LD50 in mice (mg/kg): 11.75 i.v., 4.79 i.p. (Hadidian)

MSDS

More
Less

NOGALAMYCIN Usage And Synthesis

Uses

Nogalamycin is an unusual anthracycline produced by Streptomyces nogalater var. nogalater, reported by researchers at Upjohn in 1965. Nogalamycin contains two saccharides. The neutral monosaccharide attaches to the D ring, similar to the aminoglycoside moieties of the doxorubicin class, while the second, basic saccharide attaches to the phenolic group on the A ring in the ortho position to form a unique family of hexacyclic anthracyclines. Nogalamycin is potent antibacterial and antitumor agent that interacts with DNA by intercalation.

Safety Profile

Poison by intravenous andintraperitoneal routes. Human mutation data reported. Anantibiotic. When heated to decomposition it emits toxicfumes of NOx.

More
Less

NOGALAMYCINSupplierMore

BOC Sciences
Tel:
16316197922
Email:
info@bocsci.com
Guangzhou Isun Pharmaceutical Co., Ltd
Tel:
18927568969 020-39119399-
Email:
isunpharm@qq.com
ChemStrong Scientific Co.,Ltd
Tel:
15920483169 0755-66853366-
Email:
sales@chem-strong.com
Sigma-Aldrich
Tel:
800-8193336 021-61415566-
Email:
orderCN@merckgroup.com;orderCN@merckgroup.com
Novachemistry
Tel:
+44 (0)208 191 7890
Email:
info@novachemistry.com
Basic information Safety Related Supplier