5-Bromoindole Chemical Properties

Melting point:

90-92 °C(lit.)

Boiling point:

228.5°C (rough estimate)

Density 

1.5466 (rough estimate)

refractive index 

1.6550 (estimate)

storage temp. 

-20°C

solubility 

126mg/l (calculated)

pka

16.04±0.30(Predicted)

form 

Powder or Chunks

color 

White to light brown

BRN 

112877

InChIKey

VXWVFZFZYXOBTA-UHFFFAOYSA-N

CAS DataBase Reference

10075-50-0(CAS DataBase Reference)

EPA Substance Registry System

1H-Indole, 5-bromo- (10075-50-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25-37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29339990

MSDS

• Language:EnglishProvider:5-Bromo-1H-indole
• Language:EnglishProvider:ACROS
• Language:EnglishProvider:SigmaAldrich
• Language:EnglishProvider:ALFA

5-Bromoindole Usage And Synthesis

Chemical Properties

white to light brown powder or chunks

Uses

A potential inhibitor of GSK-3

Purification Methods

Purify it by steam distillation from a faintly alkaline solution. Cool the aqueous distillate, collect the solid, dry it in a vacuum desiccator over P2O5 and recrystallise it from aqueous EtOH (35% EtOH) or pet ether/Et2O. UV in MeOH has at 279, 287 and 296nm (log 3.70, 3.69 and 3.53). The picrate has m 137-138o(dec) (from max Et2O/pet ether). [UV: Thesing et al. Chem Ber 95 2205 1962, UV and NMR: Lallemand & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 20/7 V 36.]

5-Bromoindole(10075-50-0)Related Product Information

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