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Dexamethasone Structure

Dexamethasone

Chemical Properties

Melting point 262-264 °C (lit.)
Boiling point 568.2±50.0 °C(Predicted)
alpha  75 º (c=1, dioxane)
Density  1.1283 (estimate)
refractive index  76 ° (C=1, Dioxane)
Flash point 9℃
storage temp.  2-8°C
solubility  ethanol: 1 mg/mL
pka 12.13±0.70(Predicted)
form  powder
color  off-white
Water Solubility  10 mg/100 mL (25 ºC)
Sensitive  Light Sensitive
Merck  14,2943
BRN  2066651
BCS Class 1 (CLogP), 3 (LogP)
Stability Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
InChIKey UREBDLICKHMUKA-CXSFZGCWSA-N
CAS DataBase Reference 50-02-2(CAS DataBase Reference)
NIST Chemistry Reference Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)
EPA Substance Registry System Dexamethasone (50-02-2)

Safety Information

Hazard Codes  Xi,Xn,T,F
Risk Statements  43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11
Safety Statements  36/37-45-36-26-22-16
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  TU3980000
TSCA  Yes
HS Code  29372210
Hazardous Substances Data 50-02-2(Hazardous Substances Data)
Toxicity LD50 oral in rat: > 3gm/kg

Usage And Synthesis

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