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1-Bromo-4-iodobenzene

Basic information Synthesis methods Uses Safety Related Supplier

1-Bromo-4-iodobenzene Basic information

Product Name:
1-Bromo-4-iodobenzene
CAS:
589-87-7
MF:
C6H4BrI
MW:
282.9
EINECS:
209-662-7
Mol File:
589-87-7.mol
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1-Bromo-4-iodobenzene Chemical Properties

Melting point:
89-91 °C(lit.)
Boiling point:
120-122 °C14 mm Hg(lit.)
Density 
2.2236 (rough estimate)
refractive index 
1.6618 (estimate)
Flash point:
120-122°C/14mm
storage temp. 
Store below +30°C.
solubility 
0.008g/l
form 
Crystalline Powder, Crystals or Needles
color 
White to brown
Water Solubility 
Insoluble in water.
Sensitive 
Light Sensitive
BRN 
1904545
InChIKey
UCCUXODGPMAHRL-UHFFFAOYSA-N
CAS DataBase Reference
589-87-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-bromo-4-iodo-(589-87-7)
EPA Substance Registry System
Benzene, 1-bromo-4-iodo- (589-87-7)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
Hazard Note 
Harmful/Light Sensitive
TSCA 
T
HazardClass 
IRRITANT, LIGHT SENSITIVE, IRRITANT-HARMFUL
HS Code 
29036990

MSDS

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1-Bromo-4-iodobenzene Usage And Synthesis

Synthesis methods

Industrial parabromoaniline is as raw material, by diazotization, iodo-synthesis of bromo iodobenzene. Preferred synthesis conditions: firstly 0.02mol parabromoaniline is dissolved in a mass fraction of 20% sulfuric acid medium, then reacts with 0.021molNaNO2 to generate bromophenyl diazonium sulfate at-10℃, and then chloroform and 0.021molKI is added into solution to process iodination reaction, after simple treatment bromo-iodobenzene crude product (which the bromo-iodobenzene HPLC purity 98.4%) is obtained, total yield after purification is 80%, increases by 15% than before improved. The product processes structural characterization by IR and 1HNMR. The improved method can greatly improve the purity of the crude product, this avoids the trouble of going through the column, this method is safe and easy to operate, easy to control the process, cost is lower, it is more suitable for the preparation of 1-Bromo-4-iodobenzene.
Unit: Heilongjiang University of Chemistry and Materials Science
Author: Guo Jing Bai Xuefeng Lvhong Fei

Uses

1. 1-Bromo-4-iodobenzene is used for organic synthesis.
2. Used as substrate for copper-free Sonogashira coupling reaction in aqueous acetone.
3. For the synthesis of β,β-dibromostyrene.

Chemical Properties

white to brown cryst. powder, crystals or needles

Uses

suzuki reaction

1-Bromo-4-iodobenzene Preparation Products And Raw materials

Preparation Products

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1-Bromo-4-iodobenzeneSupplierMore

Alfa Aesar Gold
Tel:
400-610-6006; 021-67582000
Email:
saleschina@alfa-asia.com
Products Intro:
Product Name:1-BroMo-4-iodobenzene, 98%
CAS:589-87-7
Package:10g Remarks:A13859
NANJING SHUNXIANG PHARMACEUTICAL TECHNOLOGY CO.,LTD. Gold
Tel:
025-86819862
Email:
nancyzong@jinchemical.com
Products Intro:
Product Name:1-Bromo-4-iodobenzene;P-BROMOIODOBENZENE
CAS:589-87-7
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Gold
Tel:
025-66099280-
Email:
cfzhang@aikonchem.com
Products Intro:
Product Name:1-BroMo-4-iodobenzene
CAS:589-87-7
Purity:95% Package:1g;5g;10g
Weifang QianJin Fine Chemical Co., Ltd. Gold
Tel:
Email:
1577399715@qq.com
Products Intro:
CAS:589-87-7
Purity:99% HPLC Package:1kg;5kg;10kg;25kg
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. Gold
Tel:
0536-2101172- ;
Email:
sdfantai@163.com;sdfantai@163.com
Products Intro:
CAS:589-87-7
Basic information Synthesis methods Uses Safety Related Supplier