Hexyl salicylate Chemical Properties

Boiling point:

290 °C(lit.)

Density 

1.04 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.505(lit.)

Flash point:

>230 °F

form 

neat

pka

8.17±0.30(Predicted)

color 

Colourless oily liquid.

Water Solubility 

0.28g/L(37 ºC)

BRN 

2453103

CAS DataBase Reference

6259-76-3(CAS DataBase Reference)

NIST Chemistry Reference

N-hexyl salicylate(6259-76-3)

EPA Substance Registry System

Hexyl salicylate (6259-76-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3082 9 / PGIII

WGK Germany 

2

RTECS 

DH2207000

Toxicity

Both the acute oral LD₅₀ value in rats and the acute dermal LD₅₀ value in rabbits exceeded 5 g/kg (Moreno, 1975).

MSDS

• Language:EnglishProvider:SigmaAldrich

Hexyl salicylate Usage And Synthesis

Chemical Properties

Colorless and transparent oil liquid

Chemical Properties

Hexyl Salicylate has been reported in carnation flower absolute . It is a colorless liquid with a green, floral, spicy odor, reminiscent of azaleas. It is used for blossom and herbal notes in perfumes, for example, in soaps, personal hygiene products, and detergents.

Occurrence

Has apparently not been reported to occur in nature.

Preparation

By methyl salicylate exchange with n-hexanol using a sodium methoxylate catalyst.

Metabolism

Because of the widespread medicinal use of salicyclic acid and its derivatives, there is an extensive literature on the metabolism and excretion of these compounds. Most esters of salicyclic acid hydrolyse to salicylic acid in the body, but this occurs more readily with the lower esters, little of the amyl ester being split. A large proportion of salicylic acid is excreted unchanged by most species; salicyluric acid, gentisic acid, and salicylglucuronides are also known to be excreted (Williams. 1959). Salicylic acid has been found to be teratogenic to rats (Koshakji. 1972).

Hexyl salicylate (6259-76-3)Related Product Information

• BETA-ZEARALENOL
• Zearalenone
• Homosalate
• Isochlortetracyclinehydrochloride
• FENCHYL SALICYLATE
• ZERANOL
• AGRIMONINE
• 2-Hydroxybenzoic acid octyl ester
• Zeranol
• Hexyl salicylate
• Dicyclohexyl phthalate
• 2-Ethylhexyl salicylate
• Sodium salicylate
• Salicylic acid
• POLY(1 6-HEXAMETHYLENE ADIPATE) AVERAG&
• Methyl salicylate
• Isoamyl o-hydroxybenzoate
• DI-N-HEXYL PHTHALATE