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D-Gluconic acid copper(II) salt

Basic information Description References Safety Related Supplier

D-Gluconic acid copper(II) salt Basic information

Product Name:
D-Gluconic acid copper(II) salt
CAS:
527-09-3
MF:
C12H22CuO14
MW:
453.84
EINECS:
208-408-2
Mol File:
527-09-3.mol
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D-Gluconic acid copper(II) salt Chemical Properties

Melting point:
155-157 °C(lit.)
refractive index 
16.5 ° (C=1, H2O)
form 
powder
optical activity
[α]26/D +15°, c = 1 in H2O
Water Solubility 
slightly soluble
Merck 
14,2640
CAS DataBase Reference
527-09-3(CAS DataBase Reference)
EPA Substance Registry System
Copper gluconate (527-09-3)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LZ5058000
TSCA 
Yes
HS Code 
29181600
Hazardous Substances Data
527-09-3(Hazardous Substances Data)

MSDS

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D-Gluconic acid copper(II) salt Usage And Synthesis

Description

D-gluconic acid copper (II) salt is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.

References

Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.

Chemical Properties

blue crystalline powder

Uses

Supplement (trace mineral).

Uses

copper gluconate is cited as having skin-conditioning and skinprotecting functions.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

D-Gluconic acid copper(II) salt Preparation Products And Raw materials

Preparation Products

Raw materials

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D-Gluconic acid copper(II) saltSupplierMore

J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Alfa Aesar
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400-610-6006; 021-67582000
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TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
Energy Chemical
Tel:
021-58432009
Email:
sales8178@energy-chemical.com
Basic information Description References Safety Related Supplier