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Copper(II) gluconate

Basic information Description References Safety Related Supplier

Copper(II) gluconate Basic information

Product Name:
Copper(II) gluconate
CAS:
527-09-3
MF:
C12H22CuO14
MW:
453.84
EINECS:
208-408-2
Mol File:
527-09-3.mol
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Copper(II) gluconate Chemical Properties

Melting point:
155-157 °C(lit.)
refractive index 
16.5 ° (C=1, H2O)
form 
powder
optical activity
[α]26/D +15°, c = 1 in H2O
Water Solubility 
slightly soluble
Merck 
14,2640
CAS DataBase Reference
527-09-3(CAS DataBase Reference)
EPA Substance Registry System
Copper gluconate (527-09-3)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LZ5058000
TSCA 
Yes
HS Code 
29181600
Hazardous Substances Data
527-09-3(Hazardous Substances Data)

MSDS

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Copper(II) gluconate Usage And Synthesis

Description

Copper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.

References

Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.

Chemical Properties

Copper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol.

Uses

Supplement (trace mineral).

Uses

copper gluconate is cited as having skin-conditioning and skinprotecting functions.

Preparation

Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

Copper(II) gluconate Preparation Products And Raw materials

Preparation Products

Raw materials

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Copper(II) gluconateSupplierMore

Shanghai Dingfen Chemical Technology Co., Ltd. Gold
Tel:
021-37590756- ;021-57450129-
Email:
369405814@qq.com;2789251452@qq.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
Alfa Aesar
Tel:
400-610-6006; 021-67582000
Email:
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
Basic information Description References Safety Related Supplier